Ward's® Detection of Hereditary Breast Cancer Kit
About this item
Can cancer be inherited?
- NGSS Life Science DCIS LS1 and LS3
- Assessments and vocabulary words target Common Core standard
- Pre and post-laboratory assessments
- Links to real world concepts
- Estimated Lab Time: 80 minutes over one to two days
- Aligned to NGSS standards (MS/HS: LS1, LS3)
Nearly a quarter of a million women in the US will develop breast cancer in a given year. Cancers may be caused by environmentally-induced or inherited genetic mutations. In this activity students will perform agarose gel electrophoresis as a molecular diagnostic test for hereditary breast cancer. Students will use the test results to predict the patient’s risk of developing cancer. Students will also learn how to analyze a family pedigree all while employing NGSS Life Science Disciplinary Core Ideas LS1 and LS3 (From Molecules to Organisms: Structures and Processes and Heredity: Inheritance and Variations of Traits). This kit includes enough materials to run 3 gels.
Pre- and Post-laboratory assessments and vocabulary words all target specific Science and Engineering Practices and common core standards. The teacher guide also contains specific "Did You Know" concepts that link the real world with scientific standards explored. A student copymaster is also included.
The kit is also available for purchase with a link to a NewPath digital lesson, which includes a variety of resources on the topic, including background information, illustrations and self-assessments.
Ordering information: Materials include “Patient” DNA samples; DNA size marker; agarose 2.0%, 200 mL; TBE running buffer 5X, 500 mL; WARD'S QUIKView DNA stain concentrate; gel staining trays; teacher's guide; and student guide. Electrophoresis chamber, power supply, micropipets with tips are materials needed but not included.
2 Options Available Below
Product Details & Documents
Can cancer be inherited?
- NGSS Life Science DCIS LS1 and LS3
- Assessments and vocabulary words target Common Core standard
- Pre and post-laboratory assessments
- Links to real world concepts
- Estimated Lab Time: 80 minutes over one to two days
- Aligned to NGSS standards (MS/HS: LS1, LS3)
Nearly a quarter of a million women in the US will develop breast cancer in a given year. Cancers may be caused by environmentally-induced or inherited genetic mutations. In this activity students will perform agarose gel electrophoresis as a molecular diagnostic test for hereditary breast cancer. Students will use the test results to predict the patient’s risk of developing cancer. Students will also learn how to analyze a family pedigree all while employing NGSS Life Science Disciplinary Core Ideas LS1 and LS3 (From Molecules to Organisms: Structures and Processes and Heredity: Inheritance and Variations of Traits). This kit includes enough materials to run 3 gels.
Pre- and Post-laboratory assessments and vocabulary words all target specific Science and Engineering Practices and common core standards. The teacher guide also contains specific "Did You Know" concepts that link the real world with scientific standards explored. A student copymaster is also included.
The kit is also available for purchase with a link to a NewPath digital lesson, which includes a variety of resources on the topic, including background information, illustrations and self-assessments.
Ordering information: Materials include “Patient” DNA samples; DNA size marker; agarose 2.0%, 200 mL; TBE running buffer 5X, 500 mL; WARD'S QUIKView DNA stain concentrate; gel staining trays; teacher's guide; and student guide. Electrophoresis chamber, power supply, micropipets with tips are materials needed but not included.
Documents
Product Family Options
Product Information
- No. of lab groupsAvailabilityPrice
- 470190-712Detection of Hereditary Breast Cancer Kit
- 470328-890Kit with NewPath Digital Resources
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.