155234 Results for: "slides-and-cover-glasses&amp"

The durable, stainless steel-lined Protector Evidence Drying Cabinet provides a secure ventilated area to dry evidence such as clothing and bedding. The cabinet’s HEPA and carbon filtered exhaust protects personnel from exposure to biohazards while eliminating nuisance odors. The spray nozzle allows the interior to be washed down for easy clean up after the cabinet has been properly disinfected. A built-in water pump aids clean up.

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Dipotassium hydrogen orthophosphate trihydrate, white crystalline powder, Reagent Grade

Supplier: MP Biomedicals

Potassium phosphate is a reagent with high buffering capacity. It occurs in several forms: monobasic, dibasic and tribasic. Most pH neutral potassium phosphate buffer solutions consist of mixtures of the monobasic and dibasic forms to varying degrees, depending on the desired pH.

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1-Octanesulfonic acid sodium salt monohydrate ≥99% for HPLC

Supplier: Spectrum Chemical Mfg. Corp.

1-Octanesulfonic Acid Sodium Salt, Monohydrate, Reagent HPLC is an ion pairing reagent which will enhance the retention of polar, ionizable compounds such as peptides and proteins. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity

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L(+)-Lysine monohydrochloride ≥98% (by titrimetric analysis on dry substance), Calbiochem®, Millipore®

Supplier: MilliporeSigma

L-Lysine hydrochloride, an essential amino acid.

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2-(4-((5-((2,6-Difluoro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)ethan-1-ol

Supplier: Aladdin Scientific

ASP5878 is a novelFGFR-selective inhibitor with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L for recombinant FGFR1, 2, 3, and 4, respectively.TargetsFGFR1 (Cell-free assay); FGFR2 (Cell-free assay); FGFR3 (Cell-free assay); FGFR4 (Cell-free assay) 0.47 nM; 0.6 nM; 0.74 nM; 3.5 nMIn vitroASP5878 inhibits the cell proliferation of HCC cell lines expressing FGF19. ASP5878 inhibits FGFR4 phosphorylation and its treatment results in the suppression of phosphorylation, mobility shift of FRS2, and suppression of ERK phosphorylation in Hep3B2.1-7 cells.In vivoOral administration of ASP5878 at 3 mg/kg induces sustained tumor regression in a subcutaneous xenograft mouse model using Hep3B2.1-7. In HuH-7, an orthotopic xenograft mouse model, ASP5878 induces complete tumor regression and dramatically extended the survival of the mice.Cell Research(from reference)Cell lines: Hep3B2.1-7 cells Concentrations: 0 to 1000 nM Incubation Time: 2 h.

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GSK-2110183

Supplier: Aladdin Scientific

Afuresertib (GSK2110183) is a potent, orally bioavailableAktinhibitor withKiof 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2. Targets Akt1 (Cell-free assay); Akt2 (Cell-free assay); Akt3 (Cell-free assay) 0.08 nM(Ki); 2 nM(Ki); 2.6 nM(Ki) In vitro Afuresertib inhibits the kinase activity of the E17K AKT1 mutant protein with EC50 of 0.2 nM. Afuresertib shows a concentration-dependent effect on multiple AKT substrate phosphorylation levels, including GSK3b, PRAS40, FOXO and Caspase 9. Overall 65% of the hematological cell lines are sensitive to afuresertib (EC50 <1 μM).