24633 Results for: "shaking+incubators"

Supplier: HETTICH INSTRUMENTS

Hettich Lab Technology's ROTINA 420 centrifuge series delivers high capacities and versatility right on the benchtop.

Supplier: HETTICH INSTRUMENTS

Hettich Lab Technology's UNIVERSAL 320 general-purpose benchtop centrifuge series provides laboratories the performance and flexibility they need to perform a variety of applications.

Supplier: Enzo Life Sciences

The HDAC3/NCOR1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC3 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions.

Supplier: SenseAnywhere

Experience the compact, robust SenseAnywhere AiroSensor 20-20-31, a wireless data logger for temperature and motion. With easy installation and maintenance, it offers up to 10 years of operation and transmits data up to 600 meters to an AccessPoint, ideal for monitoring various environments.

Supplier: Invitrogen

Immunoprecipitate using antibodies immobilized by their Fc-region glycosylation.

Supplier: HETTICH INSTRUMENTS

The Hettich Lab Technology ROTINA 380 benchtop centrifuge series delivers versatility, capacity and performance in a compact footprint.

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: TELESIS BIO

Generate seamless plasmid DNA or BAC clones without restriction digestion.

Supplier: Genetex

The classic group of Myelin basic protein (MBP) isoforms (isoforms 4-14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoforms 1-3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.

Supplier: HETTICH INSTRUMENTS

Hettich Lab Technology's ROTOFIX 32 A is a rugged, general-purpose benchtop centrifuge ideal for routine clinical, research, or industrial applications.

Supplier: Biotium

Membrane-permeant form of Fluo-4 calcium indicator.

Supplier: HETTICH INSTRUMENTS

The Hettich Lab Technology ROTANTA 460 floor-standing centrifuge series processes large sample volumes at high g-forces for high-throughput laboratories.

Supplier: Aladdin Scientific

AZD8835 ia a novel mixed inhibitor ofPI3 KαandPI3 Kδwith IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity againstPI3 Kβ(IC50=431 nM) andPI3 Kγ(IC50=90 nM). TargetsPI3 Kδ (Cell-based assay); PI3 Kα (Cell-free assay); PI3 Kγ (Cell-based assay); PI3 Kβ (Cell-based assay) 5.7 nM; 6.2 nM; 90 nM; 431 nMIn vitroAZD8835 is a potent inhibitor of PI3 Kα (wild type, E545 K and H1047 R mutations) and PI3 Kδ with excellent selectivity vs. PI3 Kβ, PI3 Kγ and an excellent general kinase selectivity.

Supplier: IBI Scientific

The unique, undulating motion of The Belly Dancer shaker is designed to provide the optimal movement for tissue culture, staining and destaining gels, Northern, Southern, or Western blotting, and immunoprecipitation

Supplier: Aladdin Scientific

BDA-366 is a small-moleculeBcl2-BH4 domain antagonist and binds BH4 with high affinity and selectivity. It directly binds to Bcl2 with high binding affinity (Ki =3.3 ± 0.73 nM). TargetsBcl2-BH4 (Cell-free assay) 3.3 nM(Ki)in vitro BDA-366 induces robust apoptosis in MM(Multiple myeloma) cell lines and primary MM cells by inducing BCL2 conformational change. BDA-366 induces a conformational change in the BCL2 molecule that converts it to a death protein, and inhibits lung cancer growthin vitro and in vivo. BDA-366 did not bind to other Bcl2 family members, including Bcl-XL, Mcl-1, or Bfl-1/A1, indicating the specificity of its Bcl2 binding.

Supplier: Eppendorf

Eppendorf® Safe-Lock 2.0 ml microtube ensure secure sample preservation. With an innovative Safe-Lock mechanism, these microtubes prevent accidental openings, providing reliability in a 2.0 ml capacity. Ideal for various applications, they combine durability, ease of use, and sample protection.

Supplier: Promega Corporation

The P450-Glo CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: BIOASSAY SYSTEMS

For quantitative determination of zinc ion Zn2+ and evaluation of drug effects on zinc metabolism

Supplier: Genetex

sRANKL is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.

Supplier: Genetex

Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.

Supplier: Promega Corporation

The P450-Glo CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: Cytiva

Eliminate lengthy sample extraction procedures using direct assay technology.

Supplier: Genetex

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

Supplier: BIOASSAY SYSTEMS

Bright bioluminescent reagent system for rapid quantitation of luciferase reporter gene expression in transfected cells and high-throughput drug screens

Supplier: Aladdin Scientific

BRD3308 is a potant and highly selective inhibitor ofHDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release. TargetsHDAC3 (Cell-free assay); HDAC1 (Cell-free assay); HDAC2 (Cell-free assay) 54 nM; 1.26 μM; 1.34 μMIn vitroBRD3308 is a derivative of the ortho-aminoanilide HDAC inhibitor CI-994 and is developed to be highly selective for inhibition of HDAC3 with an IC50 value that is 23-fold lower for HDAC3 than for HDAC1 or 22. HDAC3 selective inhibition induces expression of HIV and exposure to BRD3308 allows the recovery of latent HIV-1 from patient cells.

Supplier: WORLD PRECISION INSTRUMENTS LLC

EVOM™ Manual replaces EVOM3, EVOM2 and ERS-2.

Supplier: VWR International

USB Datalogging ULT freezer thermometer that can be used in 21 CFR 11 environments raw data is locked and may not be cleared/changed on base unit.

Supplier: Promega Corporation

The P450-Glo CYP3A4 Assay System provides a homogeneous, luminescent method for measuring CYP3A4 activity and the screening system contains a complete set of reagents for performing the assay.