24632 Results for: "shaking+incubators"

Supplier: Genetex

This is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Supplier: Promega Corporation

P450-Glo CYP1A1 Assay, 10ml

Supplier: Biotium

NucView® Caspase-3 Substrates are novel fluorescent probes that allow real-time detection of apoptosis by monitoring caspase-3/7 activity in intact cells using confocal microscopy, flow cytometry or microplate readers.

Supplier: ARBOR ASSAYS MS

Arbor Assays' Alkaline Phosphatase (ALP) Colorimetric Activity Kit provides a fast and quantitative method to measure ALP activity in serum, non-EDTA plasma, and various biological fluids. ALP catalyzes phosphate ester hydrolysis and plays a crucial role in bone metabolism, liver function, and signal transduction. The assay uses p-nitrophenyl phosphate (pNPP) as a substrate, producing a yellow product measurable at 405 nm. With a sensitivity of 0.063 mU/ml and a detection range from 1.563 to 100 mU/ml, results are obtained in 30 minutes, making it ideal for clinical research and enzyme kinetics studies.

Supplier: Invitrogen

The AminoLink Immobilization Kit contains AminoLink Coupling Resin and associated reagents sufficient to perform 5 protein immobilizations, with expected an expected yield of 2 to 20 mg protein per column.

Supplier: Thermo Scientific Chemicals

Thermo Scientific Pierce NHS-Activated Magnetic Beads enable covalent, amine-based conjugation of proteins to magnetic beads in a simple mix-and-go format for use in custom affinity purification experiments.

Supplier: Prosci

IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

Supplier: MP Biomedicals

SC-Ura is a single dropout formulation of Synthetic Complete Supplement Mixture (SC) of amino acids for S. cerevisiae growth media.

Supplier: ACRO Biosystems

This product is intended for immunocapture, biopanning and flow cytometry. This product is produced non sterile.

Supplier: Molecular Devices

Easy, automated cellular imaging and analysis. The ImageXpress® Nano Automated Imaging System enables researchers to get better data faster and improve collaborations with peers anywhere, anytime.

Supplier: VWR International

High/Low Alarm with Time/Date Stamp is an alarm tracking feature which stores in memory each alarm event, detailing when the alarm state occurred, as well as when the unit returned back to within range.

Supplier: IBI Scientific

The unique, undulating motion of The Belly Dancer shaker is designed to provide the optimal movement for tissue culture, staining and destaining gels, Northern, Southern, or Western blotting, and immunoprecipitation

Supplier: QUALITY BIOLOGICAL, INC.

McCoy’s 5A Medium is a general purpose medium that supports the propagation of many types of primary cells, established cell lines, and explants from biopsy tissues. McCoy’s 5A Medium uses a sodium bicarbonate buffer system (2.2 g/L), and therefore requires a 5–10% CO2 environment to maintain physiological pH.

Supplier: MilliporeSigma

Neo-Clear® is a non hazardous alternative to xylene. It is virtually odourless, compatible with most high purity solvents and is characterised by lower evaporation rates than xylene, making it a lower health risk.

Supplier: Prosci

Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a newtherapeutic target of metabolic syndrome.

Supplier: Prosci

GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e. g. testis, . ). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.

Supplier: TELESIS BIO

Generate seamless plasmid DNA or BAC clones without restriction digestion.

Supplier: HETTICH INSTRUMENTS

The Hettich Lab Technology MIKRO 220 microliter centrifuge series offers large capacities and high-performance for high-throughput laboratories.

Supplier: Enzo Life Sciences

An improved Fluor de Lys® HDAC assay with Fluor de Lys®-Green, a new substrate offering higher sensitivity and an excitation and emission (485/530nm) that avoids quenching and fluorescent interference from compounds absorbing in the near UV and blue range.The Fluor de Lys®-Green HDAC assay is a complete kit for measuring histone deacetylase (HDAC) activity in cell or nuclear extracts, immunoprecipitates or purified enzymes

Supplier: VWR International

USB Datalogging ULT freezer thermometer with user-defined time intervals.

Supplier: Cytiva

Whatman mixed cellulose ester membranes are composed of cellulose acetate and cellulose nitrate. These membranes are characterized by a smoother and more uniform surface than pure nitrocellulose filters.

Supplier: Prosci

FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

Supplier: Prosci

IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

Supplier: Epredia

UltraVision Quanto AP delivers higher lab profitability and better staining by supporting laboratories to select the best antibody for each test.

Supplier: ARBOR ASSAYS MS

The Palladium API Screening Fluorescent Detection Kit from Arbor Assays enables rapid quantification of palladium (Pd) contamination in active pharmaceutical ingredients (APIs). Using a highly selective fluorescent probe, the assay detects palladium concentrations across a range of 3.125 to 100 nM. Designed to evaluate scavenger methods for Pd removal, the assay requires no specialized instrumentation beyond a fluorescence plate reader. Completed in just 30 minutes, it provides a cost-effective, high-throughput alternative to ICP-MS for screening Pd levels during API purification development.

Supplier: Prosci

The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

Supplier: Prosci

Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Supplier: Prosci

Marker antibodies are useful in identification of organelles in cells, tissues, and biochemical preparations. This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.

Supplier: HETTICH INSTRUMENTS

The Hettich MIKRO 200 microliter centrifuge series is amongst the highest performing in its class.

Supplier: Aladdin Scientific

AT13148 is an oral, ATP-competitive, multi-AGC kinaseinhibitor withIC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM forAkt1/2/3,p70 S6 K, PKA, andROCKI/II, respectively. Phase 1. TargetsPKA (Cell-free assay); ROCK2 (Cell-free assay); ROCK1 (Cell-free assay); p70 S6 K (Cell-free assay); Akt1 (Cell-free assay) 15565,3 nM; 4 nM; 6 nM; 8 nM; 38 nMIn vitroAT13148, as a multi-AGC kinase inhibitor, potently inhibits proliferation with GI50 values of 1.5 to 3.8 μM across a selected panel of cancer cell lines with deregulation of PI3 K-AKT-mTOR or RAS-RAF pathways.