7709 Results for: "ice+bucket"

Supplier: Ricca Chemical

Certified reference material (CRM) for ion chromatography (IC)

Supplier: Ricca Chemical

Certified reference material (CRM) for ion chromatography (IC)

Supplier: Ricca Chemical

Certified reference material (CRM) for ion chromatography (IC)

Supplier: Abcam

Potent MCSF Receptor (CSF1R) inhibitor (IC₅₀ = 13 nM). Also inhibits Kit (IC₅₀ = 16 nM) and Flt3 (IC₅₀ = 160 nM). Highly selective (IC₅₀ >1 μM) against a panel of over 200 kinases. Inhibits MCSF Receptor-dependent proliferation (0.1 - 0.44 μM) in cell models. Inhibits glioblastoma invasion in mouse xenograft models.

Supplier: Abcam

Potent, cell-permeable cyclin-dependent kinase inhibitor (IC₅₀ values are 33 (cdk1/cyclin B), 33 (cdk2/cyclin A), 28 (cdk2/cyclin E) and 20 nM (cdk5/p35)). Inhibits ERK1 (IC₅₀ = 12.0 μM) and ERK2 (IC₅₀ = 3.1 μM). Induces cell cycle arrest at G₂/M phase (IC₅₀ = 1.25 μM). Shows apoptotic effects.

Supplier: Abcam

Potent, selective DNA (cytosine-5)-methyltransferase 3B (DNMT3B) inhibitor (IC₅₀ = 500nM). Farnesyltransferase (FTase) inhibitor (IC₅₀ = 3.2μM). Antibiotic and antimycoplasmal agent. Nanaomycin A methyl ester.

Supplier: Hardy Diagnostics

CRITERION™ Tryptic Soy Broth (TSB) with Indicator is a general growth broth for the cultivation of non-fastidious microorganisms.

Supplier: Hardy Diagnostics

CRITERION™ Azide Blood Agar Base for the isolation of staphylococci and streptococci

Supplier: Abcam

Potent, selective NF-kB inhibitor (IC₅₀ = 11 nM). Inhibits LPS-induced TNFα production (IC₅₀ = 7 nM). Reduces edema in inflammation in vivo.

Supplier: Abcam

Selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC₅₀ = 9 nM) and 4-fold greater selectivity for PKCβI (IC₅₀ = 28 nM) over Ca²+-independent PKCε (IC₅₀ = 108 nM). Enhances cardiac contractility and protection from heart failure. Prevents T-cell activation and proliferation (IC₅₀s ranging from 30-150 nM) associated with chronic inflammatory responses in vivo. Also inhibits GRK2, GRK5, and GRK6 (IC₅₀ values are 29, 3.6, and 16 μM, respectively).

Supplier: Bioss

Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.

Supplier: Desco

D-Ring fastening is ideal for bundling trays and IC tubes.

Supplier: Adipogen

VX745 is a selective inhibitor of p38alpha with an IC(50) of 10nM.

Supplier: Bioss

Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.

Supplier: Hardy Diagnostics

CRITERION™ Fraser Broth Base is used in selectively enriching and detecting Listeria spp

Supplier: Hardy Diagnostics

CRITERION™ Mycobacteria 7H11 Agar Base for the cultivation of Mycobacterium spp

Supplier: Abcam

Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).

Supplier: Abcam

Potent dopamine reuptake inhibitor (IC₅₀ = 40 nM). Inhibits noradrenaline reuptake (IC₅₀ = 800 nM). Stimulates locomotor activity and shows central effects in vivo.

Supplier: Hardy Diagnostics

CRITERION™ Violet Red Bile Glucose Agar is recommended for the detection and enumeration of Enterobacteriaceae in food and dairy products.

Supplier: Wards

A perfect tool for studying density, specific gravity, and water displacement. The 250mL polypropylene overflow can with spout only requires a catch bucket for the overflow.

Supplier: Thermo Scientific

Achieve high-resolution analysis and purification of synthetic oligonucleotides with the Thermo Scientific™ DNAPac™ PA100 column.

Supplier: Ace Glass

This Dewar condenser is for use with dry ice and other solid cooling agents

Supplier: Remco Products

This unique brush has split fiber bristles to absorb liquid so that the user is able to efficiently carry soapy water from bucket to the surface to be cleaned.

Supplier: Ace Glass

This Dewar condenser is for use with dry ice and other solid cooling agents

Supplier: Thermo Scientific

For combined ion-exchange and reversed-phase separations, the family of Thermo Scientific™ Dionex OmniPac columns delivers optimal performance and control with the advantageousof a polymeric support.

Supplier: Abcam

Highly potent, irreversible Bruton tyrosine kinase (BTK) inhibitor (IC₅₀ = 0.5nM). Inhibits autophosphorylation of BTK IC₅₀ = 11 nM), and phophorylation of PLCγ (IC₅₀ = 29 nM) and ERK (IC₅₀ = 13 nM). Potently inhbits BLK, BMS, FGR, EGFR and ITK kinases. Blocks B-cell antigen receptor (BCR) activation. Cytotoxic to chronic lymphocytic leukemia (CLL) cells.

Supplier: Adipogen

CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM.

Supplier: Thermco

These high precision liquid-in-glass mercury thermometers are hand blown, which bear graduations, numbers and letters etched into the glass and filled with and inert gas above the mercury column

Supplier: Bioss

Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.

Supplier: Adipogen

PD173955-Analog1 is a potent c-Src inhibitor with an IC(50) value of 9nM. It is also a weaker inhibitor of PDGFR, FGFR and EGFR with IC(50) values of 130nM, 110nM and 190nM respectively.