5787 Results for: "extraction"

Supplier: Contec

100% interlock knit standard weight textured polyester wipes presaturated with 70% USP grade IPA and 30% DI water.

Supplier: Rockland Immunochemical

Signal transducer and activator of transcription 1 (Stat1) belongs to a family of cytoplasmic transcription factors that can be activated by a cell surface receptor. Stat1 has two isoforms. Stat1 has been found to be inappropriately activated in many tumors. In addition to tyrosine phosphorylation, Stat1 is phosphorylated through a p38 mitogen-activated protein kinase (MAPK)-dependent pathway at Ser727 in response to IFN-g and other cellular stresses. Stat1 is localized in the cytoplasm and upon phosphorylation at Y701 is translocated to the nucleus.

Supplier: Rockland Immunochemical

Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p. This antibody is suitable for researchers interested in cell signaling, membrane biology, and growth factor research.

Supplier: SPEX

The Cole-Parmer® XP-400 X-Press® hydraulic laboratory pellet press is an automatic and fully programmable pellet press designed for repetitive pressing of sample pellets for XRF, IR, and other analytical techniques. This press can also be operated manually as a simple motorized press whose functions are under direct user control.

Supplier: Advanced Biomatrix

PhotoCol®-LAP is a methacrylated Type I collagen kit.These 3D collagen gels can be prepared at various concentrations and photocrosslinked (405nm) to provide various gel stiffness. Each kit contains 100 mg of methacrylated collagen, LAP photoinitiator, acetic acid and a neutralization solution.

Supplier: Electron Microscopy Sciences

LYNX II Automated Tissue Processor is the most unique state-of-the-art tissue processor which not only is compatible with all plastic resins but paraffin waxes as well.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for Peroxiredoxin-1(PRDX1) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.

Supplier: HUMABIOLOGICS, INC

Clinically relevant native human methacrylated bone gelatin for hydrogel and bioink applications.

Supplier: Rockland Immunochemical

SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. Anti-Setd1a Antibody is ideal for research in Epigenetics and Gene Expression.

Supplier: Promega Corporation

The BacTiter-Glo Microbial Cell Viability Assay is a homogeneous method for determining the number of viable microbial cells in culture based on quantitation of the ATP present.

Supplier: Cube Biotech

The Ultrasolute family evolved from the first amphipol A8-35 is used for highly efficient solubilization and stabilization of membrane proteins without the use of detergents while preserving their activity. They demonstrate tolerance to moderate concentrations of divalent cations and exhibit no absorption at wavelengths >250 nm.

Supplier: Rockland Immunochemical

The Anti-Pax7 antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Paired box protein Pax-7 transcription factor plays a role in myogenesis through regulation of muscle precursor cells proliferation. These genes play critical roles during fetal development and cancer growth. It is expressed specifically during the development of the nervous and muscular system. Anti-Pax7 antibody is ideal for researchers interested in developmental biology, stem cell research, cell growth and cancer research.

Supplier: GENOSENSOR CORPORATION

Quick and reliable solutions for 2019 coronavirus disease(COVID-19) and SARS-CoV-2.

Supplier: Rockland Immunochemical

The tenascins are a family of extracellular matrix proteins (ECMs). Tenascin is an extracellular matrix protein. It expressed in an unusually restricted pattern during embryogenesis and has been implicated in a variety of morphogenetic phenomena. Human hexabrachion gene(tenascin) is mapped to chromosome 9, bands q32-q34. The coding region of the hexabrachion gene spans approximately 80 kilobases of DNA and consists of 27 exons separated by 26 introns. This antibody is suitable for researchers interested in extracellular matrix antibodies.

Supplier: Rockland Immunochemical

MAS-related G-protein coupled receptor, member C, also known as MRGPRC or MRGPRX1, is a human gene. The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons. This antibody is suitable for researchers interested in neuroscience research.

Supplier: Rockland Immunochemical

The F box protein Skp2 (S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a potential molecular target for cancer therapy. This gene positively regulates the G(1)-S transition by controlling the stability of several G(1) regulators, such as the cell cycle inhibitor p27. This study provides evidence of a role for an F-box protein in oncogenesis and establishes SKP2 as a protooncogene causally involved in the pathogenesis of lymphomas. This antibody is suitable for researchers interested in cancer research.

Supplier: Rockland Immunochemical

MBD1 is a transcriptional repressor that specifically binds to methylated CpG dinucleotides in promoter sequences. MBD1 acts by recruiting a variety of histone deacetylases (HDAC’s) and chromatin remodelling factors. MBD1-dependent transcriptional repression is mediated by ATF7IP through the recruitment of factors such as the histone methyltransferase SETDB1. MBD1 probably forms a complex with SETDB1 and ATF7IP which couples DNA methylation to H3K9 trimethylation and represses transcription. Anti-MBD1 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.

Supplier: Rockland Immunochemical

The ORAI-1 gene codes for the calcium release-activated calcium (CRAC) channel subunit in humans. The CRAC channel subunit mediates calcium influx when activated by the calcium sensor, STIM1, following depletion of intracellular calcium stores. CRAC channels are the primary pathway for calcium influx in T-cells and promote the immune response to pathogens through activation of the transcription factor NFAT. Defects in this gene can be a cause of immune dysfunction due to inactivation of T-cells.

Supplier: Prosci

Cdc2 is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle. The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2.

Supplier: Rockland Immunochemical

HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the innernuclear membrane. Anti-HP1 α, β, g Antibody is ideal for research in Chromatin Remodeling and Epigenetics.

Supplier: Rockland Immunochemical

Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5b. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.

Supplier: Thermo Fisher Scientific

Get reliable around-the-clock operation ideally suited to keep your cells alive and flourishing within your working environment with Thermo Scientific™ CO₂ Resistant Shakers.

Supplier: Stemcell Technologies

Support cell attachment by preparing collagen-coated tissue cultureware or 3D collagen gels using CellAdhere™ Type I Collagen, Bovine, Solution. The most abundant type of collagen in the human body, type I collagen is a natural extracellular matrix protein that provides structural support and mimics physiological conditions, making it an ideal cultureware coating surface to support cell attachment.

Supplier: Ace Glass

This variable speed rotator is driven by a continuous-duty motor that can withstand a demanding schedule and long hours of operation.

Supplier: MP Biomedicals

Deoxyribonuclease from beef pancreas, DNase I, was first crystallized by Kunitz. It is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3'. The average chain of limit digest is a tetranucleotide. DNase I acts upon single chain DNA, and upon double-stranded DNA and chromatin.

Supplier: HUMABIOLOGICS, INC

Clinically relevant native human bone gelatin for hydrogel and bioink applications.

Supplier: Biotium

PMA (propidium monoazide) dye is a DNA modifier invented by scientists at Biotium. It is a photo-reactive dye that binds to dsDNA with high affinity. Upon photolysis with visible light, PMA dye covalently attaches itself to dsDNA.

Supplier: Rockland Immunochemical

Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a internal role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation. Anti-Jarid1c Antibody is ideal for research in Epigenetics, Gene Expression and Neuroscience.

Supplier: Rockland Immunochemical

Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5b. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.

Supplier: Rockland Immunochemical

Wdr5 belongs to the family of WD repeat proteins which are involved in different cellular processes such as cell cycle progression, signal transduction, apoptosis, and gene regulation. It is a component of the Set1A and Set1B histone H3 methylation complexes. These complexes methylate lysine 4 of H3, thereby activating gene transcription. Wdr5 interacts with H3 dimethyl K4, but not with tri or mono methylated H3K4. Anti-Wdr5 Antibody is ideal for research in Cell Cycle Control, Signal Transduction, Apoptosis, Epigenetics, Gene Expression and Cancer.