1087 Results for: "Test Lead"

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human IGF2 (Insulin Like Growth Factor 2). The assay range is from 1.56 to 100 ng/ml (Sandwich kit) with a sensitivity of 0.56 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human TNFaIP3 (Tumor Necrosis Factor Alpha Induced Protein 3). The assay range is from 78 to 5000 pg/ml (Sandwich kit) with a sensitivity of 27 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Rockland Immunochemical

Musashi2 (MSI2) is an RNA-binding protein that is highly expressed in precursor cells in the ventricular and subventricular zones of the developing mammalian CNS. Like the related MSI1, MSI2 has been suggested to be involved stem cell production and maintenance. MSI2 is the predominant MSI protein in hematopoietic stem cells, and its knockdown leads to reduced engraftment and depletion in vivo. Expression levels of MSI2 are elevated in myeloid leukemia cells lines, and MSI2 appears to cooperate with BCR-ABL1 to induce an aggressive leukemia; the level of MSI2 directly correlates with decreased survival in patients. MSI2 negatively regulates the asymmetric cell fate determinant NUMB, suggesting that this signaling pathway may provide future targets for future therapies.

Supplier: Rockland Immunochemical

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Supplier: Tonbo Biosciences

The OKT8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Supplier: Rockland Immunochemical

Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

Uniquely selective for high dipole-moment compounds such as ketones, aldehydes, nitro- or chloro-containing compounds, PAHs, unsaturated compounds, silanes, and CFCs.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Chicken IL8 (Interleukin 8). The assay range is from 15.6 to 1,000 pg/ml (Sandwich kit) with a sensitivity of 5.8 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human CFTR (Cystic Fibrosis Transmembrane Conductance Regulator). The assay range is from 0.156 to 10 ng/ml (Sandwich kit) with a sensitivity of 0.059 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human PTHrP (Parathyroid Hormone Related Protein). The assay range is from 15.6 to 1000 pg/ml (Sandwich kit) with a sensitivity of 5.5 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting General species PAF (Platelet Activating Factor). The assay range is from 37.0 to 3000 pg/ml (Competitive kit) with a sensitivity of 13.3 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human COL3a1 (Collagen Type III Alpha 1). The assay range is from 0.625 to 40 ng/ml (Sandwich kit) with a sensitivity of 0.227 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting General species VB1 (Vitamin B1). The assay range is from 3.70 to 300 ng/ml (Competitive kit) with a sensitivity of 1.63 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Rockland Immunochemical

TAB3 functions in the NF-kappaB signal transduction pathway. It and the similar and functionally redundant protein TAB2, form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.

Supplier: Rockland Immunochemical

VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.

Supplier: Prosci

Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human ProIAPP (Proislet Amyloid Polypeptide). The assay range is from 24.69 to 2000 pg/ml (Competitive kit) with a sensitivity of 8.81 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9). The assay range is from 0.312 to 20 ng/ml (Sandwich kit) with a sensitivity of 0.123 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human TRPV1 (Transient Receptor Potential Cation Channel Subfamily V, Member 1). The assay range is from 0.312 to 20 ng/ml (Sandwich kit) with a sensitivity of 0.121 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human HSD11b1 (11-Beta-Hydroxysteroid Dehydrogenase Type 1). The assay range is from 1.56 to 100 ng/ml (Sandwich kit) with a sensitivity of 0.56 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human IL8 (Interleukin 8). The assay range is from 15.6 to 1,000 pg/ml (Sandwich kit) with a sensitivity of 5.9 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human VEGFR2 (Vascular Endothelial Growth Factor Receptor 2). The assay range is from 0.625 to 40 ng/ml (Sandwich kit) with a sensitivity of 0.236 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Rabbit IL8 (Interleukin 8). The assay range is from 3.12 to 200 pg/ml (Sandwich kit) with a sensitivity of 1.16 pg/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human a1AT (Alpha to 1-Antitrypsin). The assay range is from 6.25 to 400 ng/ml (Sandwich kit) with a sensitivity of 2.83 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human LAMP2 (Lysosomal Associated Membrane Protein 2). The assay range is from 62.5 to 4000 pg/ml (Sandwich kit) with a sensitivity of 24.9 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Thermo Fisher Scientific

This general purpose, semi-micro tipped combination electrode with top-performance glass body can be used for precise pH determinations in micro volume samples.

Supplier: Wards

Large, lightweight meters, ideal for classroom demonstrations.

Supplier: Invitrogen

A versatile stabilizing solution that increases the shelf-life of purified or partially purified proteins during routine storage.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human RANkL (Receptor Activator Of Nuclear Factor Kappa B Ligand). The assay range is from 3.12 to 200 pg/ml (Sandwich kit) with a sensitivity of 1.27 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.