47164 Results for: "Stainers and Equipment, Electron Microscopy Sciences"

Supplier: MP Biomedicals

Tricine was first prepared by Good for use as a buffer for chloroplast reactions. It is structurally similar to Tris, but is much less inhibitory at high concentrations. For ATP assays using firefly luciferase, tricine buffer at 25 mM was found to be the best of ten common buffers tested.
Tricine is used as buffer component for separation of low molecular weight peptides. Tricine can be used in cryopreservation medium for the preservation of tissues and organs. Cryopreservation depends on the physical and chemical characteristics of the preservation medium used. The pH values and pK values for tricine/DMSO mixtures has been reported down to -20 °C. Tricine has been found to be an efficient scavenger of hydroxyl radicals in a study of radiation-induced membrane damage. Tricine is typically the buffer of choice in SDS-PAGE systems when separating proteins in the range of 1 to 100 kDa.
A buffer may be prepared by titrating with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH.

Supplier: BioFit

Bridgeport Series chairs boast a number of features and benefits that make them a popular choice for laboratory, healthcare, education, technical, industrial and office workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.

Supplier: BioFit

MVMT™ stands for Movement, for ergonomic seating. The chairs are developed to address the unique ergonomic needs and working postures of users in technical environments specifically for healthcare, laboratory, cleanroom and standing-desk applications.

Supplier: Ansell Healthcare

BioClean-C™ Non sterile chemotherapy protective apron with sleeves offers comfort and protection.

Supplier: Labconco

Chairs feature a durable, scratch-resistant seat mold, a welded frame with an elevated 25” chair height, and an ergonomically designed padded arm specifically contoured and angled at 10° to support the patient’s arm in a fully extended position for easier venipuncture

Supplier: MEDMIRA

Reveal® G4 Rapid HIV-1/2 Antibody Test uses MedMira Rapid Vertical Flow Technology to deliver instant results in three easy steps.

Supplier: Analytik Jena US

The UVP GelStudio touch and non-touch are gel documentation systems which use a 12 MP camera for high sensitivity imaging for DNA gels, protein gels, Coomassie Blue, GelGreen, SYBR Green and a wide range of genomic applications.

Supplier: Ansell Healthcare

Keeping wearers comfortable while offering effective protective clothing is a must, and KleenGuard™ A40 liquid and particle protection boot covers are a great solution.

Supplier: Promega Corporation

The AMP-Glo Assay is a homogeneous assay that generates a luminescent signal from any biochemical reaction that produces AMP as a reaction product.

Supplier: MCR Safety

This wizard series coat features a 0.28 mm double coating of PVC, with tough nylon scrim material layered in between.

Supplier: Epredia

Embed routine tissue samples into paraffin blocks for microtome sectioning comfortably and efficiently with the Epredia™ HistoStar™ Embedding Workstation. This workstation reduces fatigue and potential errors common when using other uncomfortable, hot or poorly illuminated embedding centers.

Supplier: BioFit

MVMT™ stands for Movement, for ergonomic seating. The chairs are developed to address the unique ergonomic needs and working postures of users in technical environments specifically for healthcare, laboratory, cleanroom and standing-desk applications.

Supplier: Ansell Healthcare

Gloves provide wearer comfort with flexibility, they can be double-donned and feature a textured surface for enhanced grip, and a beaded cuff for strength and stability on the arm. These ambidextrous cleanroom gloves with beaded cuffs can be used in medical as well as in laboratory environments

Supplier: LaMotte

Ratiometric design in innovative, waterproof, handheld meters.

Supplier: JULABO

The MAGIO™ series of cooling and heating circulators operate with a working temperature range of −50 to +300 °C and heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ circulators can be modularly and individually adapted to applications.

Supplier: Heathrow Scientific

Motor-less Stirrer that uses advanced coil technology for the strongest magnetic coupling with no moving parts!

Supplier: Sartorius

Sartorius mLINE® Mechanical Pipettors are an advanced and ergonomic choice for quality-conscious users who perform long and repetitive manual pipetting. Designed for repetitive and long-lasting procedures in order to prevent work-related hand, arm, and shoulder disorders or Repetitive Strain Injury (RSI).

Supplier: Labconco

The CApture™ BT is a spacious benchtop Cyanoacrylate (CA) evidence fuming chamber with a durable, easy-to-clean stainless steel liner

Supplier: CHEMINSTRUMENTS MS

Get precision measurements for 180° peel tests with the ChemInstruments 180° peel adhesive testing machine. The tester runs at varying speeds for added flexibility and offers a number of additional features.

Supplier: VWR International

Unit is ideal for monitoring liquids, air/gas, or semi-solids in water baths, ovens, refrigerators, incubators, and tanks.

Supplier: Adipogen

PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Supplier: Adipogen

Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.

Supplier: Adipogen

Neutrophils and eosinophils play an important role in the defence system against microbial infection. Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are known to catalyze formation of hypochlorous acid (HOCl) and hypobromous acid (HOBr). These reactive intermediates may react with proteins, lipids and nucleotides, and it has been reported to form tyrosine halogenation such as dibromotyrosine (DiBrY). DiBrY is a Br-modified tyrosine at 3- and 5- position, which is one of the major oxidative products derived from neutrophil myeloperoxidase. DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.

Supplier: Adipogen

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Supplier: Adipogen

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.

Supplier: Adipogen

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

Supplier: Adipogen

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

Supplier: Adipogen

TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to fi ve distinct receptors: TRAIL-R1 (DR4; Apo2;CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A;TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1;LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2;TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerized TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducingthe formation of the so-called multiprotein death-inducing signaling complex (DISC).

Supplier: National Public Seating

High-quality Height Adjustable Heavy Duty Vinyl Padded Swivel Steel Stool With Backrest is a great value.

Supplier: Adipogen

Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28 identified as CD80 (B7-1) and CD86 (B7-2) are immunglobulin superfamily monomeric transmembrane glycoproteins of 60kDa and 80kDa respectively. Anti-CD28 antibodies have been shown to have a strong adjuvant effect when conjugated to an immunogen. Monovalency of the CD28 receptor for its natural ligands is essential to provide costimulation without inducing responses in the absense of TCR engagement.