249206 Results for: "Shop All Science Olympiad Kits"

Supplier: Avantor Fluid Handling

Achieve high pressure, accuracy, and repeatability—with an intuitive touch-screen interface.

Supplier: Adipogen

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens. IL-2 promotes T cell proliferation and particularly naive T cells. IL-2 signaling on activated T cells is effected through a quaternary high-affinity receptor complex consisting of IL-2, IL-2Ralpha (CD25), IL-2Rbeta and IL-2Rgamma. Naive T cells are relatively insensitive to IL-2 as they only express small amounts of IL-2Rbeta and IL-2Rgamma. They only acquire sensitivity after CD25 expression, which captures the cytokine and presents it to the IL-2Rbeta and IL-2Rgamma receptors. IL-2 Superkine (Fc) is an artificial variant of IL-2 containing mutations at positions L80F / R81D / L85V / I 86V / I92F. These mutations are located in the molecule's core that acts to stabilize the structure and to give it a receptor-binding conformation mimicking native IL-2 bound to CD25. These mutations effectively eliminate the functional requirement of IL-2 for CD25 expression and elicit proliferation of T cells. Compared to IL-2, the IL-2 superkine induces superior expansion of cytotoxic T cells, leading to improved antitumour responses in vivo, and elicits proportionally less toxicity by lowering the expansion of Tregulatory cells and reducing pulmonary oedema.

Supplier: MICROPROBES FOR LIFE SCIENCE INC MS

TIP PT/IR STANDARD 51 MM 1-2 UM DIA 5MEG

Supplier: Electron Microscopy Sciences

TWEEZERS STYL N5 HIGH PREC POLSH INOX 02

Supplier: Cell Sciences

ANTIBODY CD3 CLONE MEM-57 MAB HU 100UG

Supplier: Enzo Life Sciences

MAB HSP70 N27F3-4 HU IGG1K PE 200UG IHC

Supplier: Enzo Life Sciences

MAB MOUSE CD158I 5F2 HUMAN IGG2BK 100 UL

Supplier: Enzo Life Sciences

MAB MOUSE TLR7 4F4 HUMAN IGG1K 100 UL

Supplier: Enzo Life Sciences

MAB CD21 BB6-11C9.6 PORCIN BIOTIN 500 UG

Supplier: Enzo Life Sciences

MAB MOUSE FOXO1 7H3 HUMAN IGG1 50 UG

Supplier: Enzo Life Sciences

MAB MOUSE TLR7 4F4 HUMAN IGG1K 100 UL

Supplier: Enzo Life Sciences

PAB RABBIT CD81 HUMAN IGG 100 UG F/IHC

Supplier: Enzo Life Sciences

MAB GLP-1 7-37/7-36 AMIDE FREE NT 150UG

Supplier: Meridian Life Science

SENSIFAST PROBE LO-ROX MIX 2X 5000 RXNS

Supplier: Enzo Life Sciences

HPV TYPE 6/11 PROBE DIGX RTU MIXTURE 1ML

Supplier: Revvity Health Sciences

CELL LINE APELIN FROZN HU CAMPZEN CHO-K1

Supplier: SBH SCIENCES MS

CYTOKINE GDF-15/MIC-1 H6D RECOMB HU 1MG

Supplier: Enzo Life Sciences

MAB MOUSE ZIKA VIRUS NS1 D11 IGG1 100 UG

Supplier: Enzo Life Sciences

MAB MOUSE CMV-GH 861 IGG1 100 UG F/ELISA

Supplier: Enzo Life Sciences

MAB COVID-19/MERS/SARS-COV NP IGG1 1 MG

Supplier: Enzo Life Sciences

HPV TYPE 16/18 PROBE DIGX RTU MIX 6 ML

Supplier: Enzo Life Sciences

MAB FACTOR XII HEAVY CHAIN 10-11-37 1MG

Supplier: Enzo Life Sciences

MAB MOUSE B7-H3 2A7 HUMAN IGG1K 100 UG

Supplier: Enzo Life Sciences

MAB FACTOR XII HEAVY CHAIN (10-11-5) 1MG

Supplier: Cell Sciences

FACTOR IXA-BETA NATV HU PLSM >95% 500UG

Supplier: ELECTRON MICROSCOPY SCIENCE

SHORT PIN SEM MOUNT ZEISS LEO 38MM PK10

Supplier: ELECTRON MICROSCOPY SCIENCE

SEM MINI PIN MOUNT SS 6.25MM PIN PK100

Supplier: Cadence Science

STOPCOCK 1-WAY FEM LUER LCK-FEM LUER LCK

Supplier: Cadence Science

STOPCOCK 3-WAY FEM LUER-MA LUER LF BRS

Supplier: Enzo Life Sciences

MAB MOUSE PDI 1D3 HUMAN IGG1 200UG F/IHC