296 Results for: "Protein molecular weight markers"

Supplier: Prosci

This Epithelial Membrane Antigen / EMA antibody, also called MUC1 and Mucin-1, recognizes the full-length protein in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this mAb is APDTR in the VNTR region. It reacts with the core peptide of the EMA protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the mAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This EMA antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.

Supplier: Anaspec

This peptide is a universal Bombesin synthetic ligand, binding to all 3 bombesin receptors.
Bombesin is a 14-aa peptide originally isolated from the fire-bellied toad. It has two mammalian homologs, neuromedin and Gastrin-Releasing Peptide (GRP). It binds with high affinity to the GRP receptor, a member of the G-protein-coupled receptor family. It stimulates gastrin release from G cells, and acts in the brain to stop eating behavior. Bombesin is also a tumor marker for lung small cell carcinoma, neuroblastoma, pancreatic cancer and gastric cancer.
Sequence:yQWAV-(ß-A)-HF-Nle-NH2
MW:1298.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Prosci

Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

Supplier: Bioss

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.

Supplier: Bioss

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.

Supplier: Anaspec

This peptide is histone H3 amino acid residues 1 to 21. It is phosphorylated at Thr-11 with a C-terminal GG linker, followed by a biotinylated lysine. The modification of Thr-11 via phosphorylation is processed by a number of enzymes, including protein kinase C-related kinase 1 (PRK1) and Serine/threonine-protein kinase Chk1. This has many important functions, such as the establishment of a novel chromatin marker for transcriptional regulation, and the regulation of DNA-damage induced transcriptional repression. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTARKS-pT-GGKAPRKQLA-GGK(Biotin)-NH2
MW:2802.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Adipogen

Potent anticancer compound. Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor. Anti-inflammatory. NF-kappaB inhibitor. Modulates chronic inflammatory diseases, such as type 2 diabetes, rheumatoid arthritis, inflammatory bowel disease. COX-2 and inducible nitric oxide synthase (iNOS; NOS II) inhibitor. Potent antioxidant. Protects cells from lipid peroxidation and DNA damage induced by reactive free radicals. Regulates cancer cell growth, proliferation, transformation, survival, angiogenesis, apoptosis, invasion and metastasis. Chemopreventive. Apoptosis inducer. Promotes cell cycle arrest. Modulates signal transduction pathways including JAK/STAT, MAPK, PI3K/AKT, Wnt and Notch. EGFR and HER-2 receptor signaling inhibitor. MAPKs and activator protein-1 inhibitor. mTOR suppressor. IGF-I signaling inhibitor. Proteasome inhibitor. Telomerase and DNA methyltransferase inhibitor. Selective and noncompetitive HAT inhibitor. Topoisomerase I and II inhibitor. Hedgehog signaling (Hh) modulator. PTCH and Gli1 inhibitor. Wnt signaling inhibitor. Neuroprotective. Activates HO-1 by the ARE/Nrf2 pathway, protecting neurons against oxidative damage. STAT-1 inhibitor. Shows preventive cardiovascular and metabolic (obesity, insulin resistance, hypertension and hypercholesterolemia) effects. Inhibits extracellular signal-related kinases (ERK), activates AMP-activated protein kinase (AMPK), modulates adipocyte marker proteins and down-regulates lipogenic enzymes as well as other potential targets. Fatty acid synthase (FAS) inhibitor. Autophagy stimulator.

Supplier: Invitrogen

Thermo Scientific SuperSignal Molecular Weight Protein Ladder (20 to 150K) are a ready-to-use mix of recombinant proteins with IgG-binding sites for chemiluminescent, fluorescent, chromogenic or other detection systems.

Supplier: Invitrogen

Thermo Scientific SuperSignal Enhanced Molecular Weight Protein Ladder (20 to 150K) are a ready-to-use mix of recombinant proteins with IgG-binding sites for chemiluminescent, fluorescent, chromogenic or other detection systems.

Supplier: Thermo Scientific Chemicals

Freeze-dried powder

Supplier: Edvotek

Using pre-stained LyphoProteins™, analysis with denaturing SDS vertical polyacrylamide gel electrophoresis determines subunit molecular weights.

Supplier: ACRO Biosystems

Beta 2-Microglobulin/B2M Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >98% by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 12.6 kDa, Synonym: B2M, Size: 1mg

Supplier: ACRO Biosystems

GPA33/A33 Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >96% as determined by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 24.5 kDa, Synonym: GPA33, A33, Size: 50ug

Supplier: ACRO Biosystems

Beta 2-Microglobulin/B2M Protein, Host: HEK293 Cells, Species reactivity: Cynomolgus, Purity: >95%by SDS-PAGE, Molecular Characterization: Fused with a polyhistidine tag at the C-terminus, Molecular weight of 12.6 kDa, Synonym: B2M, Size: 100ug

Supplier: ACRO Biosystems

Azurocidin/CAP37/AZU1 Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% SDS-PAGE, Molecular Characterization: Fused with 6xHis tag at the C-terminus, Molecular weight of 25 kDa, Synonym: AZU1, Azurocidin, HBP, AZAMP, AZU, Size: 1mg

Supplier: ACRO Biosystems

FABP2/I-FABP Protein, Host: E.coli, Species reactivity: Human, Purity: >95% SDS-PAGE, Molecular Characterization: His Tag is fused with a polyhistidine tag at N-terminus, Molecular weight 16 kDa, Endotoxin: <1.0 EU per ug, Synonym: FABP2, FABPI, Size: 1mg

Supplier: ACRO Biosystems

LAMP1/CD107a Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% as determined by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 39.2 kDa, Synonym: LAMP1, CD107a, Size: 1mg

Supplier: ACRO Biosystems

GPA33/A33 Protein, Host: HEK293 Cells, Species reactivity: Mouse, Purity: >95% as determined by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 24.7 kDa, Synonym: GPA33, A33, Size: 50ug

Supplier: ACRO Biosystems

Osteoactivin/GPNMB Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% by SDS-PAGE, Molecular Characterization: Fused with 6xHis tag at the C-terminus, Molecular weight of 52.9 kDa, Synonym: GPNMB, HGFIN, NMB, Osteoactivin, Size: 100ug

Supplier: ACRO Biosystems

IL-4 R alpha/CD124 Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 24.5 kDa, Synonym: IL4R, CD124, IL4RA, Size: 1mg

Supplier: ACRO Biosystems

NKp30/NCR3/CD337 Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% by SDS-PAGE, Molecular Characterization: Fused with 6xHis tag at the C-terminus, Molecular weight of 13.4 kDa, Synonym: NCR3, CD337, NKp30, 1C7, LY117, MALS, Size: 1mg

Supplier: ACRO Biosystems

Frizzled-4/FZD4 Protein, Fc Tag, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% SDS-PAGE, Molecular Characterization: Fused with a human IgG1 Fc tag at the C-terminus, Molecular weight of 42.9 kDa, Synonym: FZD4, Frizzled-4, Size: 100ug

Supplier: ACRO Biosystems

FOLR2 Protein, Host: HEK293 Cells, Species reactivity: Human, Purity: >95% by SDS-PAGE, Molecular Characterization: His Tag is Fused with a polyhistidine tag at the C-terminus, Molecular weight of 26 kDa, Synonym: FOLR2, BETA-HFR, FBP/PL-1, FR-BETA, FR-P3, FBP, Size: 100ug

Supplier: FUJIFILM IRVINE SCIENTIFIC WAKO CHE

This product is a guinea pig polyclonal antibody that reacts with MAP2. MAP2 is known as neuronal marker.

Supplier: G-Biosciences

G-Biosciences offers a selection of ready-to-screen, human, single tissue blots, from both normal and tumor tissues.

Supplier: G-Biosciences

G-Biosciences offers a selection of ready-to-screen, human, single tissue blots, from tumor tissues.

Supplier: G-Biosciences

G-Biosciences offers a selection of ready-to-screen, human, single tissue blots from normal tissues.

Supplier: BioVendor

Cystatin C is a non-glycosilated basic single-chain protein consisting of 120 amino acids with a molecular weight of 13.36 kDa and is characterized by two disulfide bonds in the carboxy-terminal region

Supplier: Enzo Life Sciences

Modulator of embryogenesis and known effector of tissue development and morphogenesis

Supplier: Biotium

CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 10,000 MW, and contains a formaldehyde-fixable free-amine group.