1150 Results for: "NMR"

Supplier: Adipogen

Mycotoxin Antibacterial against Gram-positive bacteria. Shows antimalarial and antitubercular activity. Anticancer compound. Cytotoxic against several cancer cell lines (pro-apoptotic activity). Active against plant pathogene fungi (e.g. P. oryza, Phyt. infestans). Activator of murine T lymphocytes, NK cells and macrophages.

Supplier: Adipogen

Fluorogenic substrate.

Supplier: Adipogen

Fluorogenic substrates for detecting Baeyer-Villiger monooxygenase.

Supplier: Adipogen

N-Dodecanoyl-L-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It is important to note that C12-HSL is distinct from N-3-oxo-dodecanoyl-L-homoserine lactone, which is produced at different times in biofilm development and has different cellular effects.

Supplier: Adipogen

A glycolytic intermediate formed by the isomerization of glucose-6-phosphate.

Supplier: TCI America

[1H NMR Standard for D2O Solvent] CAS Number: 2039-96-5 MDL Number: MFCD00007537 Molecular Formula: C6H16O3SSi Molecular Weight: 218.32 Purity/Analysis Method: 98.0% (T) Form: Crystal Color: White

Supplier: TCI America

CAS Number: 128-97-2 Molecular Formula: C14H8O8 Molecular Weight: 304.21 Purity/Analysis Method: 60.0% (NMR) Form: Crystal Storage Temperature: 0-10°C

Supplier: Biotium

Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2 indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2 to enter cells to quench indicator fluorescence. However, since 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2 indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.

Supplier: Adipogen

Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.

Supplier: Adipogen

Convenient substitute of o-iodoxybenzoic acid (IBX) as an oxidant. FIBX is safer, has neutral properties behaves as an equivalent to IBX in the oxidation of alcohols to ketones or aldehydes in polar solvents and shows better solubility.

Supplier: Adipogen

Inactive control compound for hedgehog signaling inhibitor 22-NHC . HCl http://www.adipogen.com/ag-cr1-3523/22-nhc-hydrochloride.html .

Supplier: Adipogen

Fluorescent marker for peptides.

Supplier: Adipogen

Very potent PARP-1 inhibitor.

Supplier: Adipogen

Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor. Apoptosis inducer. Glycogen synthase kinase (GSK-3alpha/beta) inhibitor.

Supplier: Adipogen

Necroptosis inhibitor. Does not inhibit RIP1 kinase.

Supplier: Adipogen

3-Hydroxy-hexanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

Supplier: Adipogen

Sonic hedgehog (Shh) signaling modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein.

Supplier: Adipogen

Potent antileukemia and antimyeloma compound. Apoptosis inducer. Delays tumor growth. Cyclin D2 promoter transactivation inhibitor. Inhibitor of pan-Class I PI3K isoforms.

Supplier: Adipogen

Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels.

Supplier: Adipogen

Specific cell permeable SIRT1 (sirtuin 1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer.

Supplier: Adipogen

Phosphorescent probe for measuring oxygen in very low concentrations. Luminescent marker for oxygen and pH in biomedical imaging. Used as sensitizer in the process of photon up-conversion based on triplet–triplet annihilation (TTA). Used as agent for PDT, optical limiters and other types of nonlinear optical materials.

Supplier: Adipogen

Necroptosis inhibitor. Indirect RIP1 kinase inhibitor. Cardioprotective

Supplier: Adipogen

Highly selective and potent non-peptide delta-opioid receptor agonist. Mediates downregulation of the delta-opioid receptor. Shows antidepressant-like effects. Modulates voltage-dependent sodium channels. Antinociceptive. Activates ATP-sensitive K+ channels. Enhances amphetamine-mediated dopamine efflux.

Supplier: Adipogen

Phytotoxin (inhibits root growth of seeding). Specific inhibitor of eukaryotic DNA polymerase alpha and DNA synthesis (competition with dCTP).

Supplier: MP Biomedicals

Specific histidine decarboxylase inhibitor. Anti-inflammatory. COX-1 inhibitor. Antioxidant flavonoid. Free radical scavenger. Inhibits lipid peroxidation. Antimetastatic and anticancer compound. Antiangiogenic. Anti-osteoporotic. Antibacterial and antifungal. Neuroprotective. Mono oxidase B inhibitor. Apoptosis and cell cycle arrest inducer. JNK phosphorylation inhibitor. Antispasmodic. Insulin-mimetic.

Supplier: Adipogen

Cell permeable and reversible kinesin-specific MKLP-2 (mitotic kinesin-like protein 2) inhibitor. Inhibits the recruitment of the chromosome passenger proteins survivin and aurora B to the central spindle during anaphase chromosome segregation. Moderate DYRK1A inhibitor (IC50= 5.5 µM). Lead compound.

Supplier: Adipogen

Synthetic. Originally isolated from the marine sponge Angelas mauritianus. Immunostimulant. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Protects against LPS-induced shock. Potent antitumor compound.

Supplier: Adipogen

Dihydro-beta-naphthocyclinone is an Isochromane quinone antibiotic.

Supplier: Adipogen

Salt for the generation of cationic transition metal complexes.

Supplier: Adipogen

Selective PPARgamma agonist (EC50=3 µM). Hypoglycemic agent. Angiogenesis inhibitor. Anti-inflammatory. Apoptosis inducer.