162 Results for: "MilliporeSigma TLC"

Supplier: MilliporeSigma

More soluble analog of arginine and a competitive, slowly reversible inhibitor of endothelial nitric oxide synthase (IC50 = 500nM). CAS: 51298-62-5. FW: 269.7. Purity: >=99% by TLC. Soluble in water. 100mg off-white solid.

Supplier: MilliporeSigma

A broad-based, cell-permeable serine/threonine kinase inhibitor

Supplier: MilliporeSigma

Membrane-permeable form of BAPTA

Supplier: MilliporeSigma

A DNA topoisomerase I inhibitor

Supplier: MilliporeSigma

Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 by peroxynitrite, but does not scavenge nitric oxide (NO).

Supplier: MilliporeSigma

Most active and highly stable glucocorticoid

Supplier: MilliporeSigma

Alpha-X-Gal Form White to off-white solid Cas number 1174456-59-7 Purity =98% by TLC Storage -20C A chromogenic substrate for Alpha -galactosidase. Useful for histochemical studies.

Supplier: MilliporeSigma

(OG; n-octylglucoside). White solid. HYGROSCOPIC. Purity: >= 97% by TLC. Contaminants: n-octanol: <0.05%. Absorbance (10%, H2O, 260 nm): <0.3. Aggregation number 84, CMC 20 - 25 mM. CAS 29836-26-8, M.W. 292.4. WARNING! May cause irritation.

Supplier: MilliporeSigma

(Sodium taurocholate). White solid. HYGROSCOPIC. Purity: >= 90% by TLC. Soluble in H2O. pKa 1.9. Aggregation number 4, CMC 3 - 11 mM, micellar weight 2100. RTECS WX0400000, CAS 145-42-6, M.W. 537.7.

Supplier: MilliporeSigma

An antioxidant flavonoid and a free radical scavenger

Supplier: MilliporeSigma

Major uterine luteolytic prostaglandin. A pulmonary vasoconstrictor. Inhibits nitric oxide production by the uterine tissue and increases uterine contractility.

Supplier: MilliporeSigma

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Supplier: MilliporeSigma

(Sodium taurocholate). White solid. HYGROSCOPIC. Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Purity: >= 98% by TLC. Soluble in H2O. Absorbance (100 mM, H2O, 280 nm): <0.30. pKa 1.9.

Supplier: MilliporeSigma

A derivative of papaverine that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells

Supplier: MilliporeSigma

Highly sensitive substrate for trypsin-like enzymes and granule-associated serine esterase.

Supplier: MilliporeSigma

Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2- (rate constant ~4x107 M-1s-1) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O2- oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox coupled with biological antioxidants.

Supplier: MilliporeSigma

Simvastatin, a lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation.

Supplier: MilliporeSigma

A cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties

Supplier: MilliporeSigma

CENTA™ β-lactamase substrate, is a chromogenic β-lactamase substrate for both gram-negative and gram-positive bacteria.

Supplier: MilliporeSigma

Inhibitor of calpain I (Ki=120nM), calpain II (Ki=230nM), cathepsin B (Ki=100nM), and cathepsin L (Ki=0.6nM). Inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.

Supplier: MilliporeSigma

Cell-permeable, adenine-thymine-specific fluorescent stain

Supplier: MilliporeSigma

Antiproliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. Inhibitor of UV-induced apoptosis. Strongly inhibits K562 target cell killing by human effector natural killer cells.

Supplier: MilliporeSigma

Used in the stimulation of β-galactosidase in cellular systems in which dioxane would disrupt normal cell function

Supplier: MilliporeSigma

An active metabolite of the nonsteroidal, anti-inflammatory drug sulindac (80058-684)

Supplier: MilliporeSigma

A potent, cell-permeable, and irreversible inhibitor of calpain II (k2=28,900 M-1s-1)

Supplier: MilliporeSigma

Useful in cell activation experiments when calcium dose-response data are not required.

Supplier: MilliporeSigma

(SDS; sodium dodecyl sulfate; sodium lauryl sulfate). White solid. An ionic detergent useful in electrophoretic separation of proteins and lipids. Purity: >99% by TLC. Soluble in H2O. Aggregation number 62, CMC 7-10 mM, micellar weight 18,000.

Supplier: MilliporeSigma

L-Methionine, an essential amino acid, useful as a methyl group donor.

Supplier: MilliporeSigma

Antifungal and immunosuppressant

Supplier: MilliporeSigma

A cell-permeable, non-fluorescent, and hydrophobic compound, which is rapidly hydrolyzed by intracellular esterases releasing the membrane-impermeable, hydrophilic, and intensely fluorescent calcein