49517 Results for: "Lasers and Light Sources&amp"

Supplier: Promega Corporation

Recombinant full-length human ZAK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ZAK is a member of the MAPKKK family of signal transduction molecules and mediates gamma radiation signaling leading to cell cycle arrest.

Supplier: Promega Corporation

Recombinant full-length human PKCbeta I was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKCβI is a member of the PKC family (phospholipid-dependent serine/threonine kinase) and is highly related to PKCβ II.

Supplier: Promega Corporation

Recombinant full-length human ERK2 was expressed by E. coli cells using an N-terminal GST tag and activated by MEK1 in vitro. ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs).

Supplier: Promega Corporation

Recombinant human TGF beta R2 (190-end) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. TGF beta R2 is a member of the TGF beta receptor subfamily and is a ser/thr protein kinase.

Supplier: Promega Corporation

Recombinant full-length human PKCbeta I was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKCβI is a member of the PKC family (phospholipid-dependent serine/threonine kinase) and is highly related to PKCβ II.

Supplier: Promega Corporation

Recombinant full-length human JNK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. JNK3 is a member of the c-Jun N-terminal kinases (JNKs), which are part of the mitogen-activated protein (MAP) kinase family.

Supplier: Promega Corporation

Recombinant human RET (Y791F) (amino acids 658-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Supplier: Promega Corporation

Recombinant human MINK1 (1-320) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes.

Supplier: Promega Corporation

Recombinant human EGFR (T790M) (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.

Supplier: Thermo Fisher Scientific

ClipTip technology locks tips firmly in place and ensures a complete seal on every channel with minimal tip attachment and ejection forces using Thermo Scientific™ F1-ClipTip™ Multichannel pipettes.

Supplier: Promega Corporation

Recombinant full-length human NEK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. NEK2 is closely related in its catalytic domain to the serine/threonine protein kinase NIMA of Aspergillus nidulans.

Supplier: OHAUS CORP.

Intuitive Incubating Cooling Thermal Shakers for Consistent High-Speed Shaking.

Supplier: MP Biomedicals

The FastPrep-24 5G instrument is a high-speed benchtop homogenizer offering the ultimate in speed and performance for the lysis of biological samples.

Supplier: Avantor

The NASA’s Beginning Engineering, Science and Technology (BEST) Students Kit was designed to accompany the NASA BEST Students Educator guides, an afterschool engineering club curriculum for students in grade K to 2, 3 to 5 and 6 to 8 (www.nasa.gov/audience/foreducators/best/index.html).

Supplier: Thermo Fisher Scientific

Accurately measure pH, dissolved oxygen and temperature with the Orion™ Star™ A326 pH/DO/RDO Portable Meter for high performance in challenging field tests.

Supplier: 3M Healthcare

3M™ Aqua–Pure™ under sink full flow replacement water filter cartridge AP217 is the good choice in water filtration delivering cleaner, clearer drinking water. This under sink replacement water filter cartridge is NSF listed to reduce chlorine taste and odor.

Supplier: Prosci

NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Supplier: Prosci

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Supplier: Prosci

IKK epsilon Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappa B is associated with Ikappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. Ikappa B is phosphorylated by Ikappa B kinase (IKK) complex that contains IKK alpha , IKK beta, and IKKgamma;. A novel molecule in the IKK complex was recently identified and designated IKKepsilon /IKK-i. IKK epsilon is required for the activation of NF-kappa B by PMA and T cell receptors but not by TNF alpha and IL-1. IKKepsilon /IKK-i message is expressed in a variety of tissues and is inducible by TNFalpha , IL-1, and LPS.

Supplier: Promega Corporation

Recombinant full-length human CDK2 and CyclinE1 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins. CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed.

Supplier: Thermo Scientific Chemicals

The direct magnetic IP/Co-IP kit uses NHS-chemistry to covalently immobilize IP antibodies onto magnetic beads for effective immunoprecipitation and co-immunoprecipitation.

Supplier: Eppendorf

Eppendorf Combitips® advanced, individually wrapped in 'Sterile' grade, offer exceptional purity and precision for sensitive lab procedures. Ideal for contamination-sensitive environments, these tips ensure accurate, sterile pipetting with ergonomic ease.

Supplier: ReVacc Scientific

This kit is developed for serologic test for human IgA titer of Anti-SARS-CoV-2 trimeric Spike (Wuhan Strain) antibody in serum/plasma or purified human antibody (monoclonal and polyclonal) in vitro. Antibodies of IgM and IgA class are a sign of an active infection (primary infection and reactivation) and disappear during convalescence. In some cases they can persist for several months.

Supplier: ReVacc Scientific

This kit is developed for serologic test for human IgM titer of Anti-VZV gE antibody in serum/plasma or purified human antibody (monoclonal and polyclonal) in vitro. It is for research use only. Antibodies of IgM and IgA class are a sign of an active infection (primary infection and reactivation) and disappear during convalescence. In some cases they can persist for several months.

Supplier: Electron Microscopy Sciences

EMS Shield with DAPI is an aqueous mounting medium for preserving fluorescence of tissue and cell smears.

Supplier: Bioss

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.

Supplier: Prosci

NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Supplier: Promega Corporation

Recombinant human EGFR (L858R) (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.

Supplier: Promega Corporation

Recombinant human EIF2AK2 (252-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK2 (also known as double-stranded RNA-activated protein kinase) is shown to be involved in HIV/gp120-associated neurodegeneration.

Supplier: Prosci

Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.