49542 Results for: "Lasers and Light Sources&amp"

Supplier: Promega Corporation

Recombinant human SGK1 (amino acids 60-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. SGK1 is a member of the serum- and glucocorticoid-induced protein kinase family.

Supplier: Bioss

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Supplier: Bioss

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Supplier: Bioss

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Supplier: Bioss

IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

Supplier: Bioss

IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

Supplier: Bioss

IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

Supplier: Prosci

Inhibits NF-κ-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-κ-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Supplier: Bioss

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].

Supplier: Prosci

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation.

Supplier: Lovibond

Flexible and robust reflectance spectrophotometer with QA software.

Supplier: Biosensis

NGFR/p75NTR Monoclonal antibody, Clone: 8J2, Host: Mouse, Reacts with human, mouse, rat, Isotype: IgG2a, Conjugate: ATTO 488, Immunogen: Recombinant extracellular domain (aa 29-250) of NGFR/p75NTR protein with N-ter

Supplier: Genetex

Immunoglobulin G (IgG) is one of the most abundant protein in serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defense against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions: to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Supplier: Heathrow Scientific

This compact centrifuge is ideal for fast spins with a higher RCF requirement. Ideal for PCR, microfilter cell separation, clinical and diagnostic applications, and HPLC protocols.

Supplier: BONE CLONES HOLDINGS

1.7 MYA. Male. The Australopithecus boisei Skull KNM-ER 406 was discovered by R. Leakey at Koobi Fora, Kenya, in 1969.

Supplier: GENOSENSOR CORPORATION

Your students are forensics professionals analyzing DNA collected at a crime scene.

Supplier: Ansell Healthcare

Offering a dynamic mix of protection, durability, and comfort, these gloves provide ANSI Level 2 cut protection and a lightweight ergonomic fit for a balance of safety and precision when working with small, sharp parts.

Supplier: Antibodies.com

Human Factor VII ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Factor VII in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Cayman Chemical Company

Sensitive ELISA for Vitamin D quantification.

Supplier: ReVacc Scientific

This kit is developed for serologic test for human IgG titer of Anti-NiV F and G antibody in serum/plasma or purified human antibody (monoclonal and polyclonal) in vitro.

Supplier: FIREFLYSCI, INC.

FireflySci's macro fluorometer flow through cell with detachable inlet/outlet quartz tubes.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Mouse NFkB (Nuclear Factor Kappa B). The assay range is from 0.156 to 10 ng/ml (Sandwich kit) with a sensitivity of 0.057 ng/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b, kappa isotype control antibody, FITC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, biotin-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1, kappa isotype control antibody, Alexa Fluor® 488-conjugated.

Supplier: Tonbo Biosciences

CYBRFast 1-Step RT-qPCR Lo-ROX Kit contains everything required for efficient cDNA synthesis and qPCR in a single tube using real-time instruments that support normalization with a standard ROX passive reference dye at a final concentration of 50 nM

Supplier: Tonbo Biosciences

CYBRFast 1-Step RT-qPCR Hi-ROX Kit contains everything required for efficient cDNA synthesis and qPCR in a single tube using real-time instruments that support normalization with a standard ROX passive reference dye at a final concentration of 50 nM

Supplier: Labconco

Recommended whenever perchloric acid is used in combination with other corrosive inorganic reagents.

Supplier: Anaspec

Although FITC reagents have been more often used to prepare fluoresceinated bioconjugates, the low stability of FITC bioconjugates makes some researchers use amine-reactive succinimidyl esters of carboxyfluorescein (commonly called FAM) in bioconjugations. FAM reagents give carboxamides that are more resistant to hydrolysis. We have shown that FAM reagents require less stringent reaction conditions and give better conjugation yields, and the resulted conjugates have superior stability. We noted that FITC labeled peptides tend to deteriorate more quickly than the corresponding FAM conjugates.

Supplier: Anaspec

AMCA-X, SE is one of the most popular blue fluorescent tagging molecules. It is widely used to label antibodies, proteins and small drug molecules. AMCA-X succinimidyl ester contains a seven-atom aminohexanoyl spacer, the so-called ‘X’ spacer, between the fluorophore and the reactive group. It is well known that the spacer between the fluorophore and the reactive group usually separates the fluorophore from the biomolecule to which it is conjugated, potentially reducing the quenching that typically occurs upon conjugation. In some cases, the ‘X’ spacer allows the dye to be more available for recognition by secondary detection reagents.