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119 results for "Bioconjugation Reagents"

119 Results for: "Bioconjugation Reagents"

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5-Carboxyrhodamine 110 (5-CR110) single isomer ≥95%

5-Carboxyrhodamine 110 (5-CR110) single isomer ≥95%

Supplier: AAT Bioquest

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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6-Carboxyrhodamine 110 (6-CR110) single isomer ≥95%

6-Carboxyrhodamine 110 (6-CR110) single isomer ≥95%

Supplier: AAT Bioquest

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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6-Carboxy-4,7-dichlororhodamine 110 (6-dR110) ≥95%

6-Carboxy-4,7-dichlororhodamine 110 (6-dR110) ≥95%

Supplier: AAT Bioquest

Compared to fluorescein labeling reagents such as FITC and FAM, 6-dR110 [6-carboxy-4,7-dichlororhodamine 110] reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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5-Carboxy-4,7-dichlororhodamine 110 (5-dR110) ≥95%

5-Carboxy-4,7-dichlororhodamine 110 (5-dR110) ≥95%

Supplier: AAT Bioquest

Compared to fluorescein labeling reagents such as FITC and FAM, 5-dR110 [5-carboxy-4,7-dichlororhodamine 110] reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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5(6)-TAMRA mixture of isomers ≥85%

5(6)-TAMRA mixture of isomers ≥85%

Supplier: AAT Bioquest

Tetramethylrhodamine-5-(and-6)-maleimide is an excellent reagent for preparing orange fluorescent bioconjugates through thiol modifications of peptides, nucleotides, nucleic acids and proteins.

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5-dR110 succinimidyl ester ≥75%

5-dR110 succinimidyl ester ≥75%

Supplier: AAT Bioquest

Compared to fluorescein labeling reagents such as FITC and FAM, 5-dR110 [5-carboxy-4,7-dichlororhodamine 110] reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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5(6)-Tetramethylrhodamine isothiocyanate [5(6)-TRITC] ≥90%

5(6)-Tetramethylrhodamine isothiocyanate [5(6)-TRITC] ≥90%

Supplier: AAT Bioquest

5(6)-TRITC is an amino-reactive labeling reagent that is widely used in preparing bioconjugates of proteins and nucleic acids.

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5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE] ≥95%

5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE] ≥95%

Supplier: AAT Bioquest

The succinimidyl esters of 5-TAMRA, 6-TAMRA or the mixed isomers are the primary labeling reagents for the preparation of orange fluorescent bioconjugates, including peptide, protein, nucleotide and nucleic acid conjugates, especially fluorescent antibodies and avidin derivatives used in immunochemistry.

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Tetramethylrhodamine 6-isothiocyanate chloride ≥90%

Tetramethylrhodamine 6-isothiocyanate chloride ≥90%

Supplier: AAT Bioquest

6-TRITC (also called R isomer) is the other isomer of the TRITC labeling reagent that is widely used in preparing bioconjugates of proteins and nucleic acids.

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Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Pierce™

Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Pierce™

Supplier: Invitrogen

Pierce™ Sulfo-NHS (N-hydroxysulfosuccinimide) is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.

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5(6)-Carboxyfluorescein ≥95%

5(6)-Carboxyfluorescein ≥95%

Supplier: AAT Bioquest

Carboxyfluorescein (commonly called FAM) and its amine-reactive succinimidyl esters are favored over FITC in bioconjugations.

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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester (5/6-FAM SE) ≥95%

5(6)-Carboxyfluorescein N-hydroxysuccinimide ester (5/6-FAM SE) ≥95%

Supplier: AAT Bioquest

Carboxyfluorescein (commonly called FAM) and its amine-reactive succinimidyl esters are favored over FITC in bioconjugations.

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5(6)-ROX N-succinimidyl ester mixture of isomers ≥90%

5(6)-ROX N-succinimidyl ester mixture of isomers ≥90%

Supplier: AAT Bioquest

5(6)-ROX, SE is the succinimidyl esters of 5(6)-ROX.

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Ethylene glycol diglycidyl ether (so called)

Supplier: TCI America

CAS Number: 2224-15-9 MDL Number: MFCD00005142 Molecular Formula: C8H14O4 Form: Clear Liquid Color: Colorless Flash Point (°C): 157 Specific Gravity (20/20): 1.19

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Pierce™ NHS-Azide and NHS-Phosphine Reagents, Thermo Scientific

Pierce™ NHS-Azide and NHS-Phosphine Reagents, Thermo Scientific

Supplier: Invitrogen

The NHS-Azide and NHS-Phosphine Reagents are amine-reactive compounds for derivatising primary amines of proteins or amine-coated polymer surfaces. Once a protein or surface is azide- or phosphine-labelled, the two components are mixed for effective and stable conjugation. Phosphine groups react with azides via a Staudinger reaction to produce an aza-ylide intermediate that is trapped to form a stable, covalent amide bond. Because phosphines and azides are absent from biological systems, there is minimal background labelling of macromolecules found in cells or lysates.

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5(6)-Carboxyrhodamine 110, HCl salt

Supplier: Anaspec

Although FITC reagents have been predominantly used to prepare green fluorescent bioconjugates, the low photostability and pH-dependent fluorescence of FITC bioconjugates make researchers search for alternative fluorophores in bioconjugations. Among green fluorophores, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength.

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5(6)-Carboxyfluorescein

Supplier: Anaspec

Although FITC reagents have been more often used to prepare fluoresceinated bioconjugates, the low stability of FITC bioconjugates makes some researchers use amine-reactive succinimidyl esters of carboxyfluorescein (commonly called FAM) in bioconjugations. FAM reagents give carboxamides that are more resistant to hydrolysis. We have shown that FAM reagents require less stringent reaction conditions and give better conjugation yields, and the resulted conjugates have superior stability. We noted that FITC labeled peptides tend to deteriorate more quickly than the corresponding FAM conjugates.

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N-Succinimidyl-S-acetylthioacetate ≥95% (NMR)

Supplier: Chem-Impex International

N-Succinimidyl-S-acetylthioacetate is a key reagent for bioconjugation and protein labeling, enhancing drug delivery and diagnostic applications. Ideal for researchers in chemical biology and materials science.

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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester (5/6-FAM SE)

Supplier: Anaspec

Although FITC reagents have been more often used to prepare fluoresceinated bioconjugates, the low stability of FITC bioconjugates makes some researchers use amine-reactive succinimidyl esters of carboxyfluorescein (commonly called FAM) in bioconjugations. FAM reagents give carboxamides that are more resistant to hydrolysis. We have shown that FAM reagents require less stringent reaction conditions and give better conjugation yields, and the resulted conjugates have superior stability. We noted that FITC labeled peptides tend to deteriorate more quickly than the corresponding FAM conjugates.

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N-Hydroxysuccinimide, Pierce™

Supplier: Invitrogen

Thermo Scientific Pierce NHS is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.

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Z-L-leucine-N-hydroxysuccinimide ester ≥98% (HPLC)

Z-L-leucine-N-hydroxysuccinimide ester ≥98% (HPLC)

Supplier: Chem-Impex International

Z-L-leucine-N-hydroxysuccinimide ester is a key reagent in peptide synthesis and bioconjugation, enhancing drug development and biomolecule modification. Ideal for researchers in medicinal chemistry, it offers stability and reactivity for efficient coupling reactions.

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6-Amino-D-luciferin

Supplier: Abcam

Amino analog of the common D-luciferin substrate. Cell permeable reagent that measures firefly luciferase activity. Ideal for the design of proluminescent bioconjugates (peptidase substrates) of luciferin used in ultrasensitive luminescent assays.

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Boc-L-threonine N-hydroxysuccinimide ester ≥98% (TLC)

Boc-L-threonine N-hydroxysuccinimide ester ≥98% (TLC)

Supplier: Chem-Impex International

Boc-L-threonine N-hydroxysuccinimide ester is a key reagent in peptide synthesis and bioconjugation, offering stability and enhanced reactivity for developing novel therapeutics. Ideal for researchers in medicinal chemistry and biotechnology, it streamlines complex biochemical applications.

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Z-O-tert-butyl-L-serine N-hydroxysuccinimide ester ≥99% (HPLC)

Z-O-tert-butyl-L-serine N-hydroxysuccinimide ester ≥99% (HPLC)

Supplier: Chem-Impex International

Z-O-tert-butyl-L-serine N-hydroxysuccinimide ester is a key reagent in peptide synthesis and bioconjugation, enhancing drug delivery systems and biomaterials. Ideal for researchers and pharmaceutical applications, it offers stability and selective modifications for targeted therapies.

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Dithio-bis-succinimidyl propionate (Lomant's Reagent) ≥98% (HPLC)

Supplier: Chem-Impex International

Dithio-bis-succinimidyl propionate (Lomant's Reagent) is a powerful crosslinking agent ideal for bioconjugation and protein engineering. It enables stable linkages in drug delivery systems and enhances therapeutic efficacy. Perfect for researchers in drug development and molecular biology.

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Na-Boc-Ne-2-chloro-Z-L-lysine N-hydroxysuccinimide ester ≥98% (HPLC)

Na-Boc-Ne-2-chloro-Z-L-lysine N-hydroxysuccinimide ester ≥98% (HPLC)

Supplier: Chem-Impex International

Na-Boc-Ne-2-chloro-Z-L-lysine N-hydroxysuccinimide ester is a key reagent for peptide synthesis and bioconjugation, enhancing drug development and protein modification. Ideal for researchers in pharmaceuticals and biotechnology, it offers efficient coupling reactions and improved yields.

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Fluorescein-5-maleimide ≥90% (by HPLC)

Supplier: Adipogen

Green fluorescent thiol-reactive dye (Ex/Em: 494/519nm) for bioconjugation, widely used as protein and peptide fluorescent labeling reagent, easily conjugating fluorescein. The reaction requires very mild condition and is highly specific.

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DACM ≥98% (by NMR)

Supplier: Adipogen

Excellent blue fluorescent thiol-reactive reagent (Ex/Em: 383/463nm), widely used for probing configurations of biomolecules such as proteins and create blue-fluorescent bioconjugates. The unreacted reagent is non-fluorescent and can also be used to quantitate free thiols. Shows superior fluorescence and water solubility properties than dansyl chloride.

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O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate ≥95% (HPLC)

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate ≥95% (HPLC)

Supplier: Chem-Impex International

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a powerful coupling agent for peptide synthesis and bioconjugation. Its unique properties enhance reactivity and solubility, making it ideal for advanced materials and drug design applications. Experience high efficiency and reliability in your research with this essential reagent.

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4-Maleimidobutyric acid -NHS ester ≥95% (HPLC)

Supplier: Chem-Impex International

4-Maleimidobutyric acid NHS is a key reagent for bioconjugation and protein labeling, ideal for developing targeted drug delivery systems and antibody-drug conjugates. Its unique properties enhance stability and reactivity, making it essential for researchers in biochemistry and molecular biology.

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