612655 Results for: "Animal and Human Genetics Lab Activities&amp"

Supplier: Bioss

Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Supplier: Bioss

Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Supplier: Advanced Biomatrix

Advanced BioMatrix products are recognized for purity, functionality, quality, and lot-to-lot consistency, allowing for reproducibility in research.

Supplier: Diagnostic Biosystems

The HMB45 clone reacts with a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. The HMB45-reactive antigen is present in cutaneous melanocytes, prenatal and infantile retinal pigment epithelium and melanoma cells and is thought to be oncofetal in nature. This antibody has been shown to label the majority of melanomas. Clone A103 recognizes a protein of 20 kDa, identified as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Studies have also shown that MART-1 is more sensitive than HMB45 when labeling metastatic melanomas. Tyrosinase is a key enzyme involved in the initial stages of melanin biosynthesis. Studies have shown tyrosinase to be a more sensitive marker when compared to HMB45 and MART-1. It has been shown to label a higher percentage of desmoplastic melanomas than HMB45. The combination of HMB45, MART-1 and tyrosinase make this triple antibody cocktail a first-order pan melanoma screener.

Supplier: Microgenics Corporation (Mas)

Consolidate general chemistry and serum protein QC processing into a single product offering three distinct levels with MAS™ Omni-CORE™ Controls

Supplier: Lucigen

Generate high efficiency next generation sequencing (NGS) DNA fragment libraries for Illumina sequencers starting with only 75 ng of sheared DNA input using this fast, PCR-free DNA library preparation kit.

Supplier: Biosensis

FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. DOMAIN: Death domain is responsible for interaction with RANBP9. PTM: N- and O-glycosylated. PTM: O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. PTM: Phosphorylated on serine residues. SIMILARITY: Contains 1 death domain. SIMILARITY: Contains 4 TNFR-Cys repeats.

Supplier: Lucigen

Stabilize toxic targets in favorite cloning and expression vectors.

Supplier: Advanced Biomatrix

RatCol® Type I Acid Soluble Rat Tail Collagen contains 100 mg at a concentration of approximately 4 mg/mL in a 0.02M acetic acid solution (pH 2 to 3). RatCol® collagen is soluble telo-collagen. Each product includes a bottle containing 100 mg of collagen solution accompanied with a bottle of pre-formulated neutralizing solution for the formation of a collagen gel. This collagen product is provided in user-friendly packaging for use and storage. This product is sterile filtered and is supplied as a ready to use solution. The concentration for each specific lot is provided on the product label and on a Certificate of Analysis that is available with the purchase of each product.

This product is ideal for coating of surfaces, providing preparation of thin layers for culturing cells, or use as a solid gel. RatCol® collagen is suitable for applications using a variety of cell lines including hepatocytes, fibroblasts and epithelial cells.

Supplier: Eagle Biosciences

SeroCP Quant IgA ELISA is to determine species-specific IgA antibodies to C

Supplier: Enzo Life Sciences

It is a complete assay system designed to screen inhibitors of neutrophil elastase, providing enough material to perform at least 96 assays. Neutrophil elastase, also known as leukocyte elastase (LE), is a serine protease found in polymorphonuclear neutrophils (PMNs) that functions in inflammation. It can cleave a variety of proteins, including fibrous elastin, collagen, clotting factors, TNF-α, and α1-antichymotrypsin. It has been shown to be taken up by tumor cells and accelerate tumor growth through its degradation of insulin receptor substrate-1 (IRS-1). Because of its potential roles in cancer and inflammatory diseases such as emphysema, cystic fibrosis, and atherosclerosis, it is a target for drug discovery. The kit uses the chromogenic substrate MeOSuc-Ala-Ala-Pro-Val-pNA; cleavage of p-nitroaniline (pNA) from the substrate increases absorbance at 405nm. A neutrophil elastase inhibitor, elastatinal, is included for use as a control.

Supplier: Tonbo Biosciences

The APO-DIRECT™ reagent kit provides a two color TUNEL (Terminal deoxynucleotide transferase dUTP Nick End Labeling) assay for labeling DNA breaks and total cellular DNA to detect apoptotic cells by flow cytometry. The kit contains the instructions and reagents required for measuring apoptosis in cells including: positive and negative control cells for assessing reagent performance; washing, reaction and rinsing buffers for processing individual steps in the assay; terminal deoxynucleotidyl tranferase enzyme (TdT), fluorescein isothiocyanate (FITC) deoxyuridine triphosphate (FITC-dUTP) for labeling DNA breaks and PI/RNase A solution for counter staining the total DNA.

Supplier: Aladdin Scientific

The 10× transcription buffer is the matching reaction buffer of T7 high yield transcription kit. This buffer is optimized so that one reaction can be transcribed to produce 150-200 μG RNA, which can be used for downstream applications such as RNA structure and function research, RNase protection, probe hybridization, RNAi, microinjection and in vitro translation. This product is produced with raw and auxiliary materials of medicinal specifications, and all kinds of pollution in the production process are strictly controlled. Product production and quality management procedures in line with GMP specifications ensure that the production process and all raw and auxiliary materials can be traced.

Supplier: Aladdin Scientific

10× Capping reaction buffer is a matching reaction buffer for vaccinia virus capping enzyme (gmp-m062) and mRNA cap 2 '-o methyltransferase (gmp-m072). The formula of capping reaction buffer is: 50mm Tris HCl (pH 8.0 at 25 ℃), 5mm KCl, 1mm DTT, 1mm MgCl2. This product is produced with raw and auxiliary materials of medicinal specifications, and all kinds of pollution in the production process are strictly controlled. Product production and quality management procedures in line with GMP specifications ensure that the production process and all raw and auxiliary materials can be traced.

Supplier: Eagle Biosciences

SeroCP Quant IgG ELISA is to determine species-specific IgG antibodies to C

Supplier: Invitrogen

Thermo Scientific™ Pierce™ Protein A/G Magnetic Agarose Beads provide a fast, convenient method for purification of immunoglobulins from serum, cell culture supernatant, or ascites.

Supplier: MP Biomedicals

Bovine fibrinogen has been used in studies of haemostatic therapy in surgical and massive trauma patients. These studies have shown that fibrinogen may prove to be more superior in stopping blood loss when compared to using fresh frozen plasma (FFP). It can be used for preparation of fibrin plates for analysis of fibrinolytic enzymes, a substrate for clotting assays, and study of fibrinogen degradation products.

Supplier: Eagle Biosciences

SeroMP Recombinant IgM ELISA is to detect IgM antibodies specific to M

Supplier: Eagle Biosciences

SeroMP Recombinant IgG ELISA is to detect specific IgG antibodies to M

Supplier: Eppendorf

A unique injection mold process creates a one-piece plate with virgin polypropylene wells and a rigid polycarbonate deck and skirt.

Supplier: Bioss

Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Supplier: Restek

Contains: 30042: 502.2 Calibration Mix #1 (gases); Bromomethane (methyl bromide) (74-83-9); Chloroethane (ethyl chloride) (75-00-3); Chloromethane (methyl chloride) (74-87-3); Dichlorodifluoromethane (CFC-12) (75-71-8); Trichlorofluoromethane (CFC-11) (75-69-4); Vinyl chloride (75-01-4);30431: 502.2 MegaMix Standard; Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Hexachloro-1,3-butadiene (hexachlorobutadiene) (87-68-3); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyltoluene (p-cymene) (99-87-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3);30300: 524 Calibration Mix #7A; Acetone (67-64-1); 2-Butanone (MEK) (78-93-3); 2-Hexanone (591-78-6); 4-Methyl-2-pentanone (MIBK) (108-10-1); Tetrahydrofuran (109-99-9);30304: 524 Calibration Mix #7B; Acrylonitrile (107-13-1); Allyl chloride (3-chloropropene) (107-05-1); Ethyl methacrylate (97-63-2); Methyl acrylate (96-33-3); Methyl methacrylate (80-62-6); Nitrobenzene (98-95-3); Pentachloroethane (76-01-7);30203: 524 Calibration Mix #8; Carbon disulfide (75-15-0); Chloroacetonitrile (107-14-2); 1-Chlorobutane (Butyl chloride) (109-69-3); trans-1,4-Dichloro-2-butene (110-57-6); 1,1-Dichloro-2-propanone (513-88-2); Diethyl ether (ethyl ether) (60-29-7); Hexachloroethane (67-72-1); Iodomethane (methyl iodide) (74-88-4); Methacrylonitrile (126-98-7); Methyl tert-butyl ether (MTBE) (1634-04-4); 2-Nitropropane (79-46-9); Propionitrile (107-12-0);30201: 524 Internal Standard/Surrogate Mix; 1-Bromo-4-fluorobenzene (BFB) (460-00-4); 1,2-Dichlorobenzene-d4 (2199-69-1); Fluorobenzene (462-06-6)

Supplier: Bioss

Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Supplier: DRG International

An enzyme immunoassay for the quantitative determination of caridac specific troponin I in serum.

Supplier: Lucigen

Generate the highest yields of RNA quickly and easily with these T7 RNA polymerase in vitro transcription kits.

Supplier: Advanced Biomatrix

PureCol® EZ Gel is a ready-to-use collagen solution that forms a firm gel by simply warming to 37°C in an incubator. The product consists of purified Type I collagen at a concentration of 0.5%, (~5 mg/ml), DMEM/F-12 medium and a mixture of L-glutamine and dipeptide (L-alanine-L-glutamine) to provide a long-lasting L-glutamine source for cell culture.
PureCol® EZ Gel is designed to improve gel consistency by pre-formulation of the medium and adjustment of the product to a neutral pH. This product avoids the inconsistencies in the preparation of the gel that can arise through variables of reagent addition, pH adjustment and handling conditions.

PureCol® EZ Gel is ideal for providing a firm gel and can also be used in the preparation of a thin layer for culturing cells. PureCol® EZ Gel collagen is provided in a user-friendly packaging for use and storage. This product is sterile and supplied as a ready to use solution.

Supplier: Diagnostic Biosystems

Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms' tumor. In patients with HCC, GPC3 is overexpressed in neoplastic liver tissue and elevated in serum, but is undetectable in normal liver, benign liver, and the serum of healthy donors. GPC3 expression is also found to be higher in HCC liver tissue than in cirrhotic liver or liver with focal lesions such as dysplastic nodules and areas of hepatic adenoma (HA) with malignant transformation. In the context of testicular germ cell tumors, GPC3 expression is up regulated in certain histologic subtypes, specifically yolk sac tumors and choriocarcinoma. A high level of GPC3 expression is also found in some types of embryonal tumors, such as Wilms' tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that offollicular adenoma.

Supplier: Alkali Scientific

Prepare your buffers easily with QuickSilver™ buffer powder, ensuring high-quality solutions for your laboratory experiments.

Supplier: Advanced Biomatrix

Poly-D-Lysine is a synthetic amino acid chain that is positively charged and widely used as a coating to enhance cell attachment and adhesion to both plasticware and glass surfaces. This molecule is resistant to enzymatic degradation and has been used to culture a wide variety of cell types.
The molecular weight of Poly-D-Lysine can vary significantly with lower molecular weight (30,000 Da) being less viscous and higher molecular weight (>300,000 Da) having more binding sites per molecule. This product’s molecular weight ranges from 70,000 to 150,000 Da yielding a solution viscosity for easy handling while providing sufficient binding sites for cell attachment.

Poly-D-Lysine surface coatings are designed to improve cell attachment, growth and differentiation of many cell types. Coated surfaces will often improve cell attachment in reduced or serum-free conditions. Poly-D-Lysine is supplied in a sterile 5 mg package size.

Supplier: BTNX INC.

The Rapid Response™ Plastic Collection Cup with Temperature Strip is the perfect solution for reliable urine sample collection. With a built-in temperature strip, it ensures that the sample is freshly collected, making it ideal for drug screening purposes.