612880 Results for: "Animal and Human Genetics Lab Activities&amp"

Supplier: Bioss

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Supplier: Bioss

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Supplier: Bioss

CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.

Supplier: Immunoreagents

ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  

Supplier: Rockland Immunochemical

TrueBlot® Protein G Magnetic Beads

Supplier: MP Biomedicals

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen, or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds. PEG is incompatible with phenol and may reduce the antimicrobial action of other preservatives.

Supplier: Cloud-Clone

Polyclonal Antibody to Cyclin Dependent Kinase Inhibitor 2A (CDKN2A), derived from recombinant CDKN2A(Ser3~Thr154), is reactive with Mouse/Pig.

Supplier: Antibodies.com

Mouse ICAM1 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse ICAM1 in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Mouse SFRP4 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse SFRP4 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: AZENTA US, INC

These shallow 96 well storage microplates are particularly suitable for collection and preservation of samples widely used in cell biology research, molecular biology research, and drug discovery. Clear plate, perfect for storage applications.

Supplier: Newcomer Supply

Cytokeratin 7 (CK7) control slides are for the positive immunohistochemical staining of CK7, reacting with proteins in ductal, glandular, and transitional epithelia of the urinary tract and bile duct. CK7 will also distinguish positive staining lung and breast epithelium from negative staining colon and prostate epithelial cells.

Supplier: Newcomer Supply

CD20, B-cell control slides are for the positive immunohistochemical staining of normal and neoplastic B-cells, generally located in follicles of lymph nodes and tonsils. CD20 is considered to be a pan-B-cell marker, occasionally detected in T-cell malignancies and a very strong marker of mature B-cell lymphomas.

Supplier: Newcomer Supply

Glial Fibrillary Acidic Protein (GFAP) control slides are for the positive immunohistochemical staining of GFAP, expressed in astrocytoma, glioblastoma, ependymoma, and oligodendroglioma. This marker is widely used to differentiate neoplasms of astrocytic origin from other central nervous system neoplasms.

Supplier: BIOASSAY SYSTEMS

For quantitative determination of chloride ion and evaluation of drug effects on chloride metabolism.

Supplier: Genetex

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]

Supplier: Thermo Fisher Scientific

For storage in mechanical and vapor-phase liquid nitrogen freezers, at temperatures from –196 to 121 °C (–321 to 250 °F).

Supplier: Hardy Diagnostics

A selective and differential growth medium for the cultivation, isolation, and differentiation of Vibrio spp. from food and environmental samples.

Supplier: Greiner Bio-One

Ribbed surface roller bottles come in long and short forms, and are made of high grade polystrene for stability and optical clarity, with physical surface treatment for improved cell adhesion.

Supplier: Cytiva

MabSelect™ VL protein L resin in HiScreen™ chromatography columns. A redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability.

Supplier: Greiner Bio-One

Cell culture flasks with standard screw cap/plug seal (without filter).

Supplier: Bioss

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Supplier: Bioss

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Supplier: Bioss

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq].

Supplier: Bioss

Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).

Supplier: CYTOART, INC. MS

Ra1D6 specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19- specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: Immunoreagents

ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  

Supplier: Biosensis

Leptin is secreted by white adipocytes and functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. Leptin also has several endocrine functions and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing (Ref: Entrez Gene) .

Supplier: Rockland Immunochemical

Mouse VEGF-B AccuSignal ELISA Kit

Supplier: Newcomer Supply

Epithelial membrane antigen (EMA) control slides are for the positive immunohistochemical staining of EMA, a marker of epithelial cells expressed in a variety of normal and neoplastic epithelia, including mammary and squamous epithelium and sweat glands. EMA is also expressed in a number of malignant lymphomas.

Supplier: Newcomer Supply

Alcian Blue pH 2.5, goblet cell control slides are for the positive histochemical staining of goblet cells as well as other acid epithelial mucins (sialomucin, sulfomucin). Goblet cells normally line the small intestine but are an abnormal finding in Barrett’s esophagus.