You searched for: Proteins and Peptides

Supplier: Adipogen

Human CD134 (OX40; ACT35) is an activation-associated antigen which is predominantly expressed on activated CD4 positive cells. CD134 antigen is a member of the TNF receptor family of molecules and may be involved with regulating T cell-dependent B cell proliferation and differentiation.

Supplier: Anaspec

This is a biotinylated CGRP with a long chain linker attached at the N-terminus end.
Sequence:Biotin-LC-ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (Disulfide bridge:2-7)
MW:4128.9 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

Supplier: Adipogen

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines.

Supplier: R&D Systems

The Recombinant Mouse CX3CL1/Fractalkine (Chemokine Domain) from R&D Systems is derived from E. coli. The Recombinant Mouse CX3CL1/Fractalkine (Chemokine Domain) has been validated for the following applications: Bioactivity.

Supplier: Anaspec

This 11 mer peptide myelin oligodendrocyte glycoprotein ( pMOG) ( 44–54) represents the core binding epitope for MOG-specific CD8+ T cells. This is the minimal, functionally constant, length of the MOG (35–55) peptide that binds to CD8+ MOG-specific T cells and stimulates T cell proliferation in vitro.
Sequence: FSRVVHLYRNG
MW: 1347.6 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Supplier: Cloud-Clone

This is a LRP1 recombinant protein (prokaryotic), Mouse is sequencing from Ile692~Cys962 with 97 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: R&D Systems

The Recombinant Human KIR2DL1/CD158a Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human KIR2DL1/CD158a Fc Chimera Protein has been validated for the following applications: Bioactivity.

Supplier: Anaspec

Fluorescent (FAM)-labeled ß-Amyloid (1-40), Abs/Em=494/521 nm. FAM is preferred over FITC because of its photo- and chemical stability.

Supplier: R&D Systems

The Recombinant Mouse Sonic Hedgehog/Shh (C25II) N-Terminus from R&D Systems is derived from E. coli. The Recombinant Mouse Sonic Hedgehog/Shh (C25II) N-Terminus has been validated for the following applications: Bioactivity.

Supplier: Jackson Immunoresearch Lab

Steptavidin, a bacterial protein isolated from Streptomyces avidinii, is similar to egg-white avidin in its ability to bind biotin, and has been used as a replacement for egg-white avidin because of its more favorable chemical properties.
Conjugates of streptavidin are recommended for use with Biotin-SP-conjugated antibodies and Biotin-SP-conjugated ChromPure proteins.

Supplier: R&D Systems

The Recombinant Human APRIL/TNFSF13 (HEK293-expressed) from R&D Systems is derived from HEK293. The Recombinant Human APRIL/TNFSF13 (HEK293-expressed) has been validated for the following applications: Bioactivity.

Supplier: Cloud-Clone

This is a RNase A recombinant protein (prokaryotic), Human is sequencing from Lys29~Thr156 with 90 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a HNRPA2B1 recombinant protein (prokaryotic), Human is sequencing from Arg21~Gly103 with 90 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a LY75 recombinant protein (prokaryotic), Mouse is sequencing from Cys216~Pro503 with 90 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: R&D Systems

The Recombinant Mouse CCL24/Eotaxin-2/MPIF-2 (aa 24-119) from R&D Systems is derived from E. coli. The Recombinant Mouse CCL24/Eotaxin-2/MPIF-2 (aa 24-119) has been validated for the following applications: Bioactivity.

Supplier: Adipogen

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.

Supplier: Stemcell Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf and Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilization of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways. This product is animal component-free.

Supplier: R&D Systems

The Recombinant Human CD40 Ligand/TNFSF5 (Histidine-tagged) from R&D Systems is derived from E. coli. The Recombinant Human CD40 Ligand/TNFSF5 (Histidine-tagged) has been validated for the following applications: Bioactivity.

Supplier: Cloud-Clone

This is a TMEM173 recombinant protein (prokaryotic), Mouse is sequencing from Trp160~Leu371 with 97 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: ACRO Biosystems

Human IFN-alpha 2b (K46R) Protein, Fc Tag (MALS verified), Source: expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 188, Predicted N-terminus: Cys 24, protein carries a human IgG1 Fc tag at C-terminus, Synonyms: IFNA2B, IFN-alpha 2 (alpha 2b), interferon alpha 2b, Size: 100uG

Supplier: Cloud-Clone

This is a IGF1 recombinant protein (prokaryotic), Human is sequencing from Gly49 ~ Ala118 with 95 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Adipogen

BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers.

Supplier: Cloud-Clone

This is a CTSG recombinant protein (prokaryotic), Human is sequencing from Ile21~Leu255 with 97 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a CFB active protein (prokaryotic), Mouse is sequencing from Val32~Asp157 with 97 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: R&D Systems

The Recombinant Human Cadherin-11 (CAD-11) Fc Chimera from R&D Systems is derived from NS0. The Recombinant Human Cadherin-11 (CAD-11) Fc Chimera has been validated for the following applications: Bioactivity.

Supplier: Cloud-Clone

This is a PTX3 recombinant protein (prokaryotic), Mouse is sequencing from Ile183~Ser381 with 90 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Adipogen

Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Fluorogenic substrate for calpain and papain. Peptide substrate for Ti protease from E.coli. Excitation: 360nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

Supplier: Anaspec

[Lys0]-BK(1-10) is one of the two main Bradykinin peptides that act as a mediator of inflammation with evidence showing its release at high nanomolar concentrations into the tear-film of ocular allergic patients.
Sequence:KRPPGFSPFR
MW:1188.4 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

Supplier: Adipogen

Human CD95 (APO-1; Fas) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response.

Supplier: Cloud-Clone

This is a TNC recombinant protein (prokaryotic), Mouse is sequencing from Cys174~Ser621 with 97 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.