You searched for: Proteins and Peptides

Supplier: Cloud-Clone

This is a ERa recombinant protein (prokaryotic), Human is sequencing from Ser178~Met438 with 90 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a CHRNa1 recombinant protein (prokaryotic), Human is sequencing from Ser21~Leu255 with 95 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a CYFRA21-1 recombinant protein (prokaryotic), Human is sequencing from Asp244~Leu400 with 95 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a GPX4 recombinant protein (prokaryotic), Human is sequencing from Gly74~pH e197 with 90 - 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a VEGFA active protein (prokaryotic), Human is sequencing from Pro28~Arg147 with 97 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a DSG3 recombinant protein (prokaryotic), Human is sequencing from Glu858~Ile999 with 90 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a CEA recombinant protein (prokaryotic), Human is sequencing from Pro93~Val221 with 90 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a SF3B3 recombinant protein (prokaryotic), Mouse is sequencing from Gly35~pH e210 with 95 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Adipogen

IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.

Supplier: Cloud-Clone

This is a NE recombinant protein (prokaryotic), Human is sequencing from Ile30~Gln247 with 80 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cloud-Clone

This is a RANkL active protein (eukaryotic,293F Cell), Mouse is sequencing from Arg72~Asp316 with 90 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: R&D Systems

The Recombinant Human CXCL4/PF4 (Mammalian-expressed) from R&D Systems is derived from HEK293. The Recombinant Human CXCL4/PF4 (Mammalian-expressed) has been validated for the following applications: Bioactivity.

Supplier: R&D Systems

The Recombinant Human Galectin-3 (Human Cell-expressed) from R&D Systems is derived from HEK293. The Recombinant Human Galectin-3 (Human Cell-expressed) has been validated for the following applications: Bioactivity.

Supplier: Adipogen

PARP-2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Supplier: Stemcell Technologies

Fluorescent dye conjugates for staining cell membranes of gram-positive bacteria, mammalian cells, and yeast bud scars - 1000 µg.

Supplier: R&D Systems

The Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain from R&D Systems is derived from E. coli. The Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain has been validated for the following applications: Bioactivity.

Supplier: R&D Systems

The Recombinant Human CCL3L1/MIP-1 alpha Isoform LD78 beta from R&D Systems is derived from E. coli. The Recombinant Human CCL3L1/MIP-1 alpha Isoform LD78 beta has been validated for the following applications: Bioactivity.

Supplier: R&D Systems

The Recombinant Human TGF-beta 1 (Human Cell-expressed) from R&D Systems is derived from HEK293. The Recombinant Human TGF-beta 1 (Human Cell-expressed) has been validated for the following applications: Bioactivity.

Supplier: Anaspec

This peptide is amino acids 311 to 325 fragment of the influenza virus nucleoprotein (NP). This bona fide MHC class II restricted epitope from influenza virus was used to study the host immunoresponse during the infection. This peptide elicits the strongest gamma interferon (IFN-gamma) production in the intracellular cytokine assays. It does not stimulate CD8 T-cells in mice.
Sequence:QVYSLIRPNENPAHK
MW:1767 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Cloud-Clone

This is a CA125 recombinant protein (prokaryotic), Human is sequencing from Arg13977~Ser14117 with 95 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Stemcell Technologies

Stimulating T cells with VZV (gE) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. VZV (gE) Peptide Pool is a lyophilized mixture of 153 peptides from the envelope glycoprotein E (gE) of Varicella-zoster virus (VZV; strain Dumas), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 - 623 on gE. gE is essential for VZV replication (Mo et al., 2002) and may contribute to viral pathogenesis by facilitating epithelial cell-cell contacts (Mo et al., 2000). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.

Supplier: Anaspec

This peptide, Exendin-4, has a biotin on the N-terminus. Exendin-4, an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Exendin-4 shares a 53% sequence homology with GLP-1. Derived from Gila monster, Heloderma suspectum, Exendin-4 has a longer half life than GLP-1 in the plasma, thus making it a more potent insulinotropic agent.
Sequence: Biotin-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
MW: 4412.9 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Supplier: Anaspec

The short peptide RGDS (Arg-Gly-Asp-Ser) is a synthetic cell adhesion factor. RGDS is known to mediate cell adhesion to several extracellular matrix components as well as cell–cell interactions. The RGDS peptide has been shown to interact directly with and activates caspases 8 and 9, which indicates an unexpected pro-apoptotic effect due to an intracellular action.
Sequence:RGDS
MW:433.4 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec

This sequence corresponds to the N-terminus of histone H3, spanning amino acids 1 to 25, amidated. Histones are small proteins (11–22 kDa) that mediate the folding of DNA into chromatin.
Sequence:ARTKQTARKSTGGKAPRKQLATKAA-NH2
MW:2625.1 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec

An H-2Db restricted epitope, this peptide is amino acids 61 to 80 fragment of the lymphocytic choriomeningitis virus (LCMV) pre-glycoprotein polyprotein GP complex. LCMV has been routinely used for the study of adaptive immune responses to viral infection.
Sequence:GLNGPDIYKGVYQFKSVEFD
MW:2276.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Adipogen

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of two ligands for programmed death 1 (PD-1), a member of the CD28 family of immunoreceptors. CD274 is widely expressed in several organs such as heart, skeletal muscle, placenta and lung, and in lower amounts in thymus, spleen, kidney and liver. CD274 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. CD274 expression is also induced in dendritic cells and keratinocytes after IFN-gamma stimulation. CD274 expression is also upregulated in a variety of tumor cell lines. Interaction of CD274 with PD-1 results in inhibition of TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. The CD274 - PD-1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.

Supplier: Stemcell Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.). This product is animal component-free.

Supplier: Stemcell Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.).

Supplier: Stemcell Technologies

Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines. All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds. Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3. It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva and O'Garra). IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells. IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.).

Supplier: Adipogen

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. Recently a novel role for IL-36alpha in the pathogenesis of intestinal inflammation has been reported.