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A scientist holding a bottle of fluid and operating equipment as part of the mAbs production process

Optimizing the mAbs Production Process

Support your mAbs production process with end-to-end solutions that support upstream cell culture, downstream purification, formulation, and final fill. Simplify monoclonal antibody process development with scalable, high-performance fluid management solutions and bioprocess ingredients, including raw materials and resins, to maximize yield and reduce risk at every step.

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Monoclonal Antibodies (mAbs) Production Process | Avantor

Build Consistency Into Every Batch

In the mAbs production process, inconsistencies between batches risk failure, yield loss, and regulatory delays. Avantor helps reduce that risk with scalable fluid management technologies and global supply continuity so you can confidently move from development to production.

Close up of an open bottle of Avantor Seradigm Sera

Cell viability and mAb yield start with consistent upstream performance. Avantor offers high-purity raw materials, cell culture media supplements, and feeds designed to support robust clone selection and upstream scalability.

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Scientist inspecting and operating a piece of equipment in a buffer management facility

Buffers are central to an efficient mAbs production process. Avantor’s raw materials, fluid management technologies, and expertise make a difference in your buffer management process by helping you improve operational efficiency, reduce facility footprint, and reduce risk.

Optimize Your Buffer Preparation

Close up of gloved hands holding a vial

Using the J.T.Baker® BAKERBOND® PROchievA protein A affinity resin with select additives, Avantor designed an integrated mAbs purification process that significantly improves throughput while removing critical impurities.

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Two scientists in full protective gear walking in a downstream processing facility

Formulation success relies on low-variability buffers, excipients, and cleanroom-ready packaging. Avantor helps ensure your monoclonal antibody process development is ready for fill-finish and regulatory submission.

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Related Products & Services

Scientists in full protective gear using Avantor fluid management systems in a laminar flow hood

Aseptic, scalable fluid management technologies, including pumps, single-use systems, and assemblies, support consistent flow, reduced contamination, and efficiency at every mAbs production stage.

Explore Fluid Management Solutions

A scientist in full protective gear holding a bottle of chemicals

Buffers, salts, and excipients support mAb stability and quality. Select from cGMP-grade chemicals designed to reduce variability and meet global regulatory standards.                                    

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Two scientists inspecting and operating equipment for mAbs processing

Avantor Services help improve upstream and downstream performance from media optimization to purification so you can scale faster with fewer disruptions.                                    

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